专题:Alzheimer's disease research and treatments

This cluster of papers focuses on the research and mechanisms related to Alzheimer's disease, including the amyloid hypothesis, tau pathology, protein misfolding, neuroinflammation, synaptic dysfunction, oxidative stress, genetic associations, Aß oligomers, neurodegeneration, and therapeutic strategies.
最新文献
Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease

article Full Text OpenAlex

Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer’s disease retina

article Full Text OpenAlex

Ageing promotes microglial accumulation of slow-degrading synaptic proteins

article Full Text OpenAlex

Plasma but not salivary p-Tau181 reflects Alzheimer's disease in a Latin American Cohort

article Full Text OpenAlex

Heterogeneous Dynamics of the Fuzzy Coat of Full-Length Phospho-Mimetic Tau Fibrils

article Full Text OpenAlex

Amyloid-β and Tau in Alzheimer’s disease: pathogenesis, mechanisms, and interplay

article Full Text OpenAlex

Viscoelasticity and interface properties of multi-component condensates govern protein sequestration and suppression of amyloid formation

article Full Text OpenAlex

Type 3 Diabetes: A Molecular Link Between Cerebral Insulin Resistance and Neurodegeneration via AGE–RAGE Signaling

article Full Text OpenAlex

Down syndrome with Alzheimer's disease brains have increased iron and associated lipid peroxidation consistent with ferroptosis

article Full Text OpenAlex

The evolving landscape of Alzheimer’s disease therapy: From Aβ to tau

article Full Text OpenAlex

近5年高被引文献
Lecanemab in Early Alzheimer’s Disease

article Full Text OpenAlex 4756 FWCI529.9877

Copper induces cell death by targeting lipoylated TCA cycle proteins

article Full Text OpenAlex 4330 FWCI482.5213

Donanemab in Early Symptomatic Alzheimer Disease

article Full Text OpenAlex 2239 FWCI404.0624

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup

article Full Text OpenAlex 1776 FWCI704.7517

Hallmarks of neurodegenerative diseases

review Full Text OpenAlex 1478 FWCI266.6456

Role of neuroinflammation in neurodegeneration development

review Full Text OpenAlex 1262 FWCI226.0614

Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease

article Full Text OpenAlex 1248 FWCI138.8372

Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets

review Full Text OpenAlex 1164 FWCI145.0571

Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future

review Full Text OpenAlex 792 FWCI140.7988

A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Nanotherapeutics

review Full Text OpenAlex 768 FWCI84.7719