专题：Osteoarthritis Treatment and Mechanisms

This cluster of papers focuses on the pathophysiology of osteoarthritis, with an emphasis on cartilage degradation, inflammation, joint mechanics, and potential therapeutic approaches such as cartilage regeneration using mesenchymal stem cells. It also covers the role of chondrocytes, matrix metalloproteinases, and synovitis in the development and progression of osteoarthritis.
最新文献
Isolation, purification and characterization of lipocartilage in mice

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A disease-severity-responsive nanoparticle enables potent ghrelin messenger RNA therapy in osteoarthritis

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Retraction: Zoledronic acid generates a spatiotemporal effect to attenuate osteoarthritis by inhibiting potential Wnt5a-associated abnormal subchondral bone resorption

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Retraction: Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway

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Early Anterior Cruciate Ligament Reconstruction Mitigates the Development of Posttraumatic Osteoarthritis in a Murine Anterior Cruciate Ligament Rupture Model

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Reactive oxygen species-associated molecular landscape uncovers diagnostic and immune features in osteoarthritis

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Responsiveness and interpretability of the Italian version of the Knee Outcome Survey − Activities of Daily Living Scale in patients with knee disorders

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Prevalence of knee osteoarthritis in the Chinese population, 2013–2023: a systematic review and meta-analysis

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Effects of Blood‐Flow Restricted Resistance Exercise Versus Neuromuscular Exercise on Self‐Perceived Knee Pain, Function, Quality of Life, and Objective Measures of Functional Performance and Pain Sensitization in Adults With Knee Osteoarthritis—A Randomized Controlled Trial

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Ctsk + Osteoclasts Orchestrate Condylar Morphogenesis via Hypoxic Lysosome

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近5年高被引文献
Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021

article Full Text OpenAlex 1287 FWCI539.64239503

Prevalence Trends of Site‐Specific Osteoarthritis From 1990 to 2019: Findings From the Global Burden of Disease Study 2019

article Full Text OpenAlex 1036 FWCI256.96735847

Osteoarthritis: pathogenic signaling pathways and therapeutic targets

review Full Text OpenAlex 914 FWCI379.59636152

Synovial inflammation in osteoarthritis progression

review Full Text OpenAlex 841 FWCI209.39945372

Obesity, Inflammation, and Immune System in Osteoarthritis

review Full Text OpenAlex 389 FWCI86.1778976

Current understanding of osteoarthritis pathogenesis and relevant new approaches

review Full Text OpenAlex 337 FWCI40.73589129

Inflammaging and Osteoarthritis

review Full Text OpenAlex 332 FWCI82.30002568

AAOS Clinical Practice Guideline Summary: Management of Osteoarthritis of the Knee (Nonarthroplasty), Third Edition

article Full Text OpenAlex 292 FWCI70.72265204

Knee Osteoarthritis: Epidemiology, Pathogenesis, and Mesenchymal Stem Cells: What Else Is New? An Update

review Full Text OpenAlex 290 FWCI119.00858902

Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits

article Full Text OpenAlex 289 FWCI75.12515224