专题：Inflammatory Bowel Disease

This cluster of papers explores the genetics, epidemiology, pathogenesis, and treatment of inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. It covers topics such as host-microbe interactions, genetic susceptibility loci, immune system involvement, therapeutic targets, and the global burden of these diseases.
最新文献
Inflammatory bowel diseases: pathological mechanisms and therapeutic perspectives

article Full Text OpenAlex

Tucidinostat ameliorates DSS-induced ulcerative colitis by inhibiting cellular senescence, modulating the p53 signaling pathway and cell cycle, and restoring the gut microbiota-metabolite Axis

article Full Text OpenAlex

Fecal microbial and metabolic signatures in children with very early onset inflammatory bowel disease

article Full Text OpenAlex

Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease

article Full Text OpenAlex

Medical management of inflammatory bowel diseases

review Full Text OpenAlex

Preclinical stages of Crohn’s disease defined by faecal calprotectin in asymptomatic first-degree relatives: screening framework for prevention trials

article Full Text OpenAlex

A multi-mineral intervention to improve disease-related and mechanistic biomarkers in ulcerative colitis patients: Results from a randomized trial

article Full Text OpenAlex

Efficacy and safety of IL-23p19 and IL-12/23p40 inhibitors in moderate-to-severe Crohn’s disease: a systematic review and network meta-analysis

article Full Text OpenAlex

Hedyotis diffusa willd-scutellaria barbata herbal Pair ameliorates colitis-associated colorectal cancer progression by modulating the gut microbiota and the PPARγ/NF-κB pathway

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Nrf2 as a Molecular Guardian of Redox Balance and Barrier Integrity in IBD

article Full Text OpenAlex

近5年高被引文献
Ulcerative colitis

review Full Text OpenAlex 1234 FWCI392.5899

Upadacitinib as induction and maintenance therapy for moderately to severely active ulcerative colitis: results from three phase 3, multicentre, double-blind, randomised trials

article Full Text OpenAlex 554 FWCI96.9562

Ulcerative Colitis in Adults

review Full Text OpenAlex 548 FWCI174.6251

Twenty-first Century Trends in the Global Epidemiology of Pediatric-Onset Inflammatory Bowel Disease: Systematic Review

review Full Text OpenAlex 527 FWCI95.8328

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global Burden of Disease Study 2019

review Full Text OpenAlex 513 FWCI163.5651

The Gut Microbiota in Inflammatory Bowel Disease

review Full Text OpenAlex 509 FWCI40.6952

Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

review Full Text OpenAlex 493 FWCI83.3037

Pathophysiology of Inflammatory Bowel Disease: Innate Immune System

review Full Text OpenAlex 466 FWCI77.9246

Gut microbiota, inflammatory bowel disease and colorectal cancer

review Full Text OpenAlex 412 FWCI34.708

Crohn's disease

review Full Text OpenAlex 392 FWCI223.1032