专题：Genomics and Chromatin Dynamics

This cluster of papers focuses on the regulation of chromatin structure and function, including topics such as histone modifications, transcriptional regulation, enhancers, DNA elements, 3D genome organization, and nucleosome positioning. The research covers a wide range of molecular mechanisms involved in controlling gene expression and epigenetic processes.
最新文献
Translation efficiency covariation identifies conserved coordination patterns across cell types

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The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate

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Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy

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Retrospective and multifactorial single-cell profiling reveals sequential chromatin reorganization during X inactivation

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Nucleosome spacing can fine-tune higher-order chromatin assembly

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DNA Methylation Reflects Cis‐Genetic Differentiation Across the European Crow Hybrid Zone

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Structural basis of RECQL5-induced RNA polymerase II transcription braking and subsequent reactivation

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Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function

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Condensin II activation by M18BP1

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Scalable screening of ternary-code DNA methylation dynamics associated with human traits

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近5年高被引文献
JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

article Full Text OpenAlex 1593 FWCI106.778

YaHS: yet another Hi-C scaffolding tool

article Full Text OpenAlex 1535 FWCI144.221

Single-cell chromatin state analysis with Signac

article Full Text OpenAlex 1251 FWCI73.701

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

article Full Text OpenAlex 1079 FWCI68.643

Effective gene expression prediction from sequence by integrating long-range interactions

article Full Text OpenAlex 816 FWCI50.276

Histone post-translational modifications — cause and consequence of genome function

review Full Text OpenAlex 732 FWCI24.651

A genomic mutational constraint map using variation in 76,156 human genomes

article Full Text OpenAlex 716 FWCI196.207

Base-resolution models of transcription-factor binding reveal soft motif syntax

article Full Text OpenAlex 545 FWCI36.111

Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease

article Full Text OpenAlex 515 FWCI31.52

STREME: accurate and versatile sequence motif discovery

article Full Text OpenAlex 447 FWCI29.263