专题：Genomics and Chromatin Dynamics

This cluster of papers focuses on the regulation of chromatin structure and function, including topics such as histone modifications, transcriptional regulation, enhancers, DNA elements, 3D genome organization, and nucleosome positioning. The research covers a wide range of molecular mechanisms involved in controlling gene expression and epigenetic processes.
最新文献
JCVI: A versatile toolkit for comparative genomics analysis

article Full Text OpenAlex

The PNUTS phosphatase complex controls transcription pause release

article Full Text OpenAlex

RNA Polymerase II Activity Control of Gene Expression and Involvement in Disease

review Full Text OpenAlex

Stabilization of the hexasome intermediate during histone exchange by yeast SWR1 complex

article Full Text OpenAlex

Enhancers: A Focus on Synthetic Biology and Correlated Gene Expression

review Full Text OpenAlex

Designing realistic regulatory DNA with autoregressive language models

article Full Text OpenAlex

Expansionin situgenome sequencing links nuclear abnormalities to hotspots of aberrant euchromatin repression

preprint Full Text OpenAlex

Developmental and housekeeping transcriptional programs display distinct modes of enhancer-enhancer cooperativity in Drosophila

article Full Text OpenAlex

Diffusion within the synaptonemal complex can account for signal transduction along meiotic chromosomes

article Full Text OpenAlex

Chromatin Transcription Elongation – A Structural Perspective

review Full Text OpenAlex

近5年高被引文献
JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

article Full Text OpenAlex 1979 FWCI180.43499041

YaHS: yet another Hi-C scaffolding tool

article Full Text OpenAlex 1827 FWCI225.09348995

Single-cell chromatin state analysis with Signac

article Full Text OpenAlex 1536 FWCI107.67579968

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

article Full Text OpenAlex 1260 FWCI96.55710298

Effective gene expression prediction from sequence by integrating long-range interactions

article Full Text OpenAlex 1028 FWCI70.80854218

A genomic mutational constraint map using variation in 76,156 human genomes

article Full Text OpenAlex 974 FWCI349.93137231

Histone post-translational modifications — cause and consequence of genome function

review Full Text OpenAlex 923 FWCI118.76173745

Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease

article Full Text OpenAlex 623 FWCI52.56997829

Base-resolution models of transcription-factor binding reveal soft motif syntax

article Full Text OpenAlex 613 FWCI49.64400547

STREME: accurate and versatile sequence motif discovery

article Full Text OpenAlex 549 FWCI45.64517595