专题：Microbial Natural Products and Biosynthesis

This cluster of papers focuses on the exploration of natural products, particularly from microbial sources, as potential sources of new drugs. It covers various aspects such as genome sequencing, biosynthetic gene clusters, secondary metabolites, and their role in drug discovery. The cluster also emphasizes the significance of marine natural products and the potential of endophytic fungi in providing bioactive compounds for pharmaceutical applications.
最新文献
Nature meets machine: the AI renaissance in natural product drug discovery

review Full Text OpenAlex

Rethinking Nature’s Pharmacy: AI Era and Natural Product Drug Discovery

review Full Text OpenAlex

Recent Advances in Pleuromutilin Derivatives as Antimicrobial Agents (2015–2025)

review Full Text OpenAlex

Artificial Intelligence as a Catalyst for Antimicrobial Discovery: From Predictive Models to De Novo Design

review Full Text OpenAlex

BiG-SCAPE 2.0 and BiG-SLiCE 2.0: scalable, accurate and interactive sequence clustering of metabolic gene clusters

article Full Text OpenAlex

Harnessing secondary metabolites of endophytic microbes: a next-generation biopesticide for crop disease management

review Full Text OpenAlex

Marine natural products

review Full Text OpenAlex

Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi

article Full Text OpenAlex

Biodiversity-Driven Natural Products and Bioactive Metabolites

review Full Text OpenAlex

Antifungal Biocontrol in Sustainable Crop Protection: Microbial Lipopeptides, Polyketides, and Plant-Derived Agents

review Full Text OpenAlex

近5年高被引文献
antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation

article Full Text OpenAlex 2321 FWCI364.2267

Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review

review Full Text OpenAlex 1231 FWCI24.0907

antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation

article Full Text OpenAlex 710 FWCI404.0256

Identification of antimicrobial peptides from the human gut microbiome using deep learning

article Full Text OpenAlex 500 FWCI61.1909

A microbial supply chain for production of the anti-cancer drug vinblastine

article Full Text OpenAlex 479 FWCI31.444

Artificial intelligence for natural product drug discovery

review Full Text OpenAlex 469 FWCI7.966

Discovery of a structural class of antibiotics with explainable deep learning

article Full Text OpenAlex 468 FWCI67.0783

Streptomyces: The biofactory of secondary metabolites

review Full Text OpenAlex 463 FWCI11.2314

MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

article Full Text OpenAlex 449 FWCI54.2786

Bioactive Secondary Metabolites from Plant Sources: Types, Synthesis, and Their Therapeutic Uses

article Full Text OpenAlex 444 FWCI29.4022