专题：Drug Solubulity and Delivery Systems

This cluster of papers focuses on the advances in drug delivery systems, including the use of cyclodextrins, solid dispersions, nanosuspensions, and lipid-based formulations to improve drug solubility and enhance oral delivery. It also explores the application of the Biopharmaceutics Classification System and the development of amorphous pharmaceuticals for improved drug absorption. The research covers a wide range of topics related to pharmaceutical materials and gastrointestinal drug absorption.
最新文献
Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs

article Full Text OpenAlex

Thermally-Induced Supersaturation Approach for Optimizing Drug Loading and Biopharmaceutical Properties of Supersaturated Lipid-Based Formulations: Case Studies with Ibrutinib and Enzalutamide

article Full Text OpenAlex

Effects of hydroxyapatite size on the drug release characteristics of drug-containing coatings

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Inclusion complex of 2-phenylethanol in β-cyclodextrin: Preparation, characterization, computational study and evaluation of antinociceptive activity

article Full Text OpenAlex

Quality-by-Design-Driven Nanostructured Lipid Scaffold of Apixaban: Optimization, Characterization, and Pharmacokinetic Evaluation

article Full Text OpenAlex

Enrofloxacin Pharmaceutical Formulations through the Polymer-Free Electrospinning of β-Cyclodextrin–oligolactide Derivatives

article Full Text OpenAlex

Establishing Virtual Bioequivalence and Clinically Relevant Specifications for Omeprazole Enteric-Coated Capsules by Incorporating Dissolution Data in PBPK Modeling

article Full Text OpenAlex

Functionality of wet-granulated disintegrant in comparison to directly incorporated disintegrant in a poorly water-soluble tablet matrix

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Experimental analysis and modeling of aprepitant (an antiemetic drug for chemotherapy) solubility in subcritical water with/without co-solvent

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Intestinal Absorption Site-Guided Development and Evaluation of Oral Disintegrating Controlled Release Tablets of Mirabegron

article Full Text OpenAlex

近5年高被引文献
A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives

review Full Text OpenAlex 1056 FWCI137.5440885

Advances in Oral Drug Delivery

review Full Text OpenAlex 718 FWCI56.76274433

Advances in drug delivery systems, challenges and future directions

review Full Text OpenAlex 628 FWCI88.6437128

Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics

review Full Text OpenAlex 483 FWCI58.69593028

Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

review Full Text OpenAlex 441 FWCI33.71297718

Drug release study of the chitosan-based nanoparticles

review Full Text OpenAlex 421 FWCI28.65064514

Cyclodextrins inclusion complex: Preparation methods, analytical techniques and food industry applications

review Full Text OpenAlex 350 FWCI42.53328281

Recent advances in polymeric transdermal drug delivery systems

review Full Text OpenAlex 315 FWCI23.91144068

Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review

review Full Text OpenAlex 285 FWCI45.71632655

Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

review Full Text OpenAlex 274 FWCI20.78787411