专题：Genetic Associations and Epidemiology

This cluster of papers encompasses a wide range of topics in genomic studies, including genome-wide association analyses, genetic variation, haplotype mapping, population genetics, Mendelian randomization, polygenic risk scores, gene expression, and the study of complex diseases. It explores methods for analyzing genetic data and understanding the genetic basis of various traits and diseases.
最新文献
Polygenic prediction of body mass index and obesity through the life course and across ancestries

article Full Text OpenAlex

AI-HOPE: An AI-Driven conversational agent for enhanced clinical and genomic data integration in precision medicine research

article Full Text OpenAlex

Structural variation detection and association analysis of whole‐genome‐sequence data from 16,543 Alzheimer's disease sequencing project subjects

article Full Text OpenAlex

Detecting monogenic obesity: a systematic exome-wide workup of over 500 individuals

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Generative prediction of causal gene sets responsible for complex traits

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Neuroimaging endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders

article Full Text OpenAlex

Understanding indirect assortative mating and its intergenerational consequences for educational attainment

article Full Text OpenAlex

Genetic and physiological insights into satiation variability predict responses to obesity treatment

article Full Text OpenAlex

Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research

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Mighty oaks from little acorns: High-quality genomes of underrepresented populations enhance health equity in precision medicine

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近5年高被引文献
Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization

review Full Text OpenAlex 2652 FWCI80.685

FinnGen provides genetic insights from a well-phenotyped isolated population

article Full Text OpenAlex 2642 FWCI758.807

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

article Full Text OpenAlex 2021 FWCI344.39

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

article Full Text OpenAlex 1795 FWCI200.975

New insights into the genetic etiology of Alzheimer’s disease and related dementias

article Full Text OpenAlex 1709 FWCI291.768

A cross-population atlas of genetic associations for 220 human phenotypes

article Full Text OpenAlex 1649 FWCI168.248

Mendelian randomization

article Full Text OpenAlex 1449 FWCI247.308

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

article Full Text OpenAlex 1389 FWCI77.678

Genome-wide association studies

article Full Text OpenAlex 1252 FWCI147.689

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

review Full Text OpenAlex 1212 FWCI42.601