专题：Developmental Biology and Gene Regulation

This cluster of papers explores the Notch signaling pathway and its role in various aspects of development, including gene regulation, stem cell maintenance, embryonic development, and vertebrate origins. It also delves into the implications of Notch signaling in tumorigenesis and evolutionary biology.
最新文献
The Notch ligand Jagged1 plays a dual role in cochlear hair cell regeneration

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Background of the Research

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The emergence of chordin-like1 in gnathostomes may have contributed to the evolution of paired appendages

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Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential

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Role of TGF-β3 in Regulating Neural Crest Cell Fate and Craniofacial Development: Insights From Zebrafish Models

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Notch4 but not Notch1 yin-yang dimerization correlates with condensate formation but not transcriptional activity

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Distal enhancers loop to proximal enhancers, not to promoters

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Caudal fin shape imprinted during late zebrafish embryogenesis is re-patterned by SONIC hedgehog

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An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification

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Notch4 is essential for the maintenance of vascular homeostasis in the young adult pituitary posterior lobes

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近5年高被引文献
Enhancer redundancy in development and disease

review Full Text OpenAlex 215 FWCI5.592

Biophysics of Notch Signaling

review Full Text OpenAlex 176 FWCI4.245

Control of osteoblast regeneration by a train of Erk activity waves

article Full Text OpenAlex 159 FWCI15.848

Notch Signaling in Vascular Endothelial Cells, Angiogenesis, and Tumor Progression: An Update and Prospective

review Full Text OpenAlex 158 FWCI3.718

Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues

article Full Text OpenAlex 155 FWCI13.666

Transcriptional coupling of distant regulatory genes in living embryos

article Full Text OpenAlex 147 FWCI14.165

Origins, Development, and Compartmentation of the Granule Cells of the Cerebellum

article Full Text OpenAlex 144 FWCI9.651

The Role of Neurod Genes in Brain Development, Function, and Disease

article Full Text OpenAlex 140 FWCI9.106

Independence of chromatin conformation and gene regulation during Drosophila dorsoventral patterning

article Full Text OpenAlex 139 FWCI10.118

GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo

article Full Text OpenAlex 124 FWCI8.328