专题：Epigenetics and DNA Methylation

This cluster of papers explores the diverse mechanisms and functional implications of epigenetic modifications, including DNA methylation, histone modification, and chromatin remodeling. It delves into the role of these modifications in various biological processes such as cancer development, transgenerational inheritance, and environmental responses. Additionally, it discusses the potential applications of epigenetic therapy.
最新文献
The impact of the Val16Ala polymorphism of the Sod2 gene on the development and severity of stroke

article Full Text OpenAlex

Histone and non-histone lactylation: molecular mechanisms, biological functions, diseases, and therapeutic targets

review Full Text OpenAlex

A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors

article Full Text OpenAlex

Maternal iron deficiency causes male-to-female sex reversal in mouse embryos

article Full Text OpenAlex

Implications of gut microbiota-mediated epigenetic modifications in intestinal diseases

review Full Text OpenAlex

Lactate dehydrogenase B facilitates disulfidptosis and exhaustion of tumour-infiltrating CD8+ T cells

article Full Text OpenAlex

Unravelling cysteine-deficiency-associated rapid weight loss

article Full Text OpenAlex

Data- and knowledge-derived functional landscape of human solute carriers

article Full Text OpenAlex

The solute carrier superfamily interactome

article Full Text OpenAlex

The genetic interaction map of the human solute carrier superfamily

article Full Text OpenAlex

近5年高被引文献
Hallmarks of Cancer: New Dimensions

review Full Text OpenAlex 3605 FWCI231.725

Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

review Full Text OpenAlex 1552 FWCI51.726

Cancer metabolism: looking forward

review Full Text OpenAlex 1405 FWCI36.76

Genome-wide association studies

article Full Text OpenAlex 1278 FWCI148.083

Hallmarks of response, resistance, and toxicity to immune checkpoint blockade

review Full Text OpenAlex 1216 FWCI34.833

Macrophage Polarization States in the Tumor Microenvironment

review Full Text OpenAlex 1185 FWCI26.697

The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource

article Full Text OpenAlex 1182 FWCI197.698

Macrophages in immunoregulation and therapeutics

review Full Text OpenAlex 1109 FWCI57.737

Large-scale integration of the plasma proteome with genetics and disease

article Full Text OpenAlex 1059 FWCI97.743

The cancer metabolic reprogramming and immune response

review Full Text OpenAlex 903 FWCI22.198