专题：Epigenetics and DNA Methylation

This cluster of papers explores the diverse mechanisms and functional implications of epigenetic modifications, including DNA methylation, histone modification, and chromatin remodeling. It delves into the role of these modifications in various biological processes such as cancer development, transgenerational inheritance, and environmental responses. Additionally, it discusses the potential applications of epigenetic therapy.
最新文献
An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes

article Full Text OpenAlex

Advancing Epigenetic Combination Therapy in Oncology: Multifunctional Nano-Drug Delivery Systems for Synergistic Efficacy and Precision Modulation

review Full Text OpenAlex

Advancing CNS tumor diagnostics with expanded DNA methylation-based classification

article Full Text OpenAlex

The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin

article Full Text OpenAlex

Epigenetic drugs in cancer therapy: mechanisms, immune modulation, and therapeutic applications

article Full Text OpenAlex

Resistance of first-line targeted drugs in hepatocellular carcinoma: the epigenetic regulation mechanisms

article Full Text OpenAlex

A metabolic atlas of mouse aging

article Full Text OpenAlex

Nutrigenomics meets multi-omics: integrating genetic, metabolic, and microbiome data for personalized nutrition strategies

article Full Text OpenAlex

From concept to clinic: a roadmap for DNA methylation biomarkers in liquid biopsies

article Full Text OpenAlex

Genetic elements promote retention of extrachromosomal DNA in cancer cells

article Full Text OpenAlex

近5年高被引文献
Hallmarks of Cancer: New Dimensions

article Full Text OpenAlex 8842 FWCI983.6606

Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

review Full Text OpenAlex 2206 FWCI169.5825

Macrophages in immunoregulation and therapeutics

review Full Text OpenAlex 1880 FWCI298.0572

The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource

article Full Text OpenAlex 1687 FWCI298.3213

Autophagy and autophagy-related pathways in cancer

review Full Text OpenAlex 1270 FWCI263.942

Cell cycle regulation: p53-p21-RB signaling

review Full Text OpenAlex 1210 FWCI120.2953

Pancreatic cancer: Advances and challenges

review Full Text OpenAlex 1149 FWCI259.2067

Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

review Full Text OpenAlex 1051 FWCI83.1015

DunedinPACE, a DNA methylation biomarker of the pace of aging

article Full Text OpenAlex 901 FWCI68.4677

Microbiome differential abundance methods produce different results across 38 datasets

article Full Text OpenAlex 897 FWCI72.8011