专题：Epigenetics and DNA Methylation

This cluster of papers explores the diverse mechanisms and functional implications of epigenetic modifications, including DNA methylation, histone modification, and chromatin remodeling. It delves into the role of these modifications in various biological processes such as cancer development, transgenerational inheritance, and environmental responses. Additionally, it discusses the potential applications of epigenetic therapy.
最新文献
The solute carrier superfamily interactome

article Full Text OpenAlex

The genetic interaction map of the human solute carrier superfamily

article Full Text OpenAlex

Data- and knowledge-derived functional landscape of human solute carriers

article Full Text OpenAlex

The pathogenesis and therapeutic implications of metabolic reprogramming in renal cell carcinoma

review Full Text OpenAlex

Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity

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Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion

article Full Text OpenAlex

Hypoxia-induced phase separation of ZHX2 alters chromatin looping to drive cancer metastasis

article Full Text OpenAlex

Crosstalk between metabolism and epigenetics during macrophage polarization

review Full Text OpenAlex

Histone lactylation enhances GCLC expression and thus promotes chemoresistance of colorectal cancer stem cells through inhibiting ferroptosis

article Full Text OpenAlex

Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer

article Full Text OpenAlex

近5年高被引文献
Hallmarks of Cancer: New Dimensions

review Full Text OpenAlex 3364 FWCI240.598

Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

review Full Text OpenAlex 1302 FWCI49.174

Cancer metabolism: looking forward

review Full Text OpenAlex 1273 FWCI36.773

Genome-wide association studies

article Full Text OpenAlex 1147 FWCI146.431

Hallmarks of response, resistance, and toxicity to immune checkpoint blockade

review Full Text OpenAlex 1109 FWCI34.833

Macrophage Polarization States in the Tumor Microenvironment

review Full Text OpenAlex 1067 FWCI26.7

The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource

article Full Text OpenAlex 1043 FWCI194.158

Large-scale integration of the plasma proteome with genetics and disease

article Full Text OpenAlex 898 FWCI97.155

The genetics of obesity: from discovery to biology

review Full Text OpenAlex 866 FWCI33.519

Macrophages in immunoregulation and therapeutics

review Full Text OpenAlex 853 FWCI52.909