专题：Mitochondrial Function and Pathology

This cluster of papers focuses on the dynamics of mitochondria, the production and regulation of reactive oxygen species (ROS), and their implications in various biological processes such as aging, neurodegenerative diseases, and metabolic regulation. The papers cover topics including mitochondrial fusion and fission, oxidative stress, mitochondrial dysfunction, and the role of mitochondria in cell death.
最新文献
Mitochondrial transfer from immune to tumor cells enables lymph node metastasis

article Full Text OpenAlex

Synaptic mitochondrial oxidative stress drives individual variability in age-related cognitive decline in mice

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Disrupting α-Synuclein–ClpP interaction restores mitochondrial function and attenuates neuropathology in Parkinson’s disease models

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Targeting mitochondrial structure and dynamics for therapeutic intervention in cancer

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Reactive Oxygen Species Across Death Pathways: Gatekeepers of Apoptosis, Ferroptosis, Pyroptosis, Paraptosis, and Beyond

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Mitochondrial dysfunction-related metabolite methylmalonic acid is associated with decreased cognitive performance

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Polycomb Repressive Complex 1 and USP16 localize to the mitochondrion and influence its function

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MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death

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SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis

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TurboID-based proximity labeling identifies novel germline proteins that maintain E granule integrity and small RNA homeostasis in C. elegans

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近5年高被引文献
Copper induces cell death by targeting lipoylated TCA cycle proteins

article Full Text OpenAlex 4106 FWCI688.20383872

Lactate metabolism in human health and disease

review Full Text OpenAlex 1100 FWCI148.60047185

Mitochondrial dynamics in health and disease: mechanisms and potential targets

review Full Text OpenAlex 868 FWCI161.16191383

Mitochondrial dysfunction in cell senescence and aging

review Full Text OpenAlex 803 FWCI141.62263504

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

review Full Text OpenAlex 796 FWCI97.47077312

Mitochondrial dysfunction: mechanisms and advances in therapy

article Full Text OpenAlex 686 FWCI328.96934921

Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling

article Full Text OpenAlex 611 FWCI74.0876331

Mitochondrial signal transduction

review Full Text OpenAlex 532 FWCI67.31882942

Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction

review Full Text OpenAlex 487 FWCI93.39221504

Mechanisms of BCL-2 family proteins in mitochondrial apoptosis

review Full Text OpenAlex 484 FWCI89.86447729