专题：Mitochondrial Function and Pathology

This cluster of papers focuses on the dynamics of mitochondria, the production and regulation of reactive oxygen species (ROS), and their implications in various biological processes such as aging, neurodegenerative diseases, and metabolic regulation. The papers cover topics including mitochondrial fusion and fission, oxidative stress, mitochondrial dysfunction, and the role of mitochondria in cell death.
最新文献
NINJ1 regulates plasma membrane fragility under mechanical strain

article Full Text OpenAlex

A mitochondrial disease model is generated and corrected using engineered base editors in rat zygotes

article Full Text OpenAlex

ROMO1 overexpression protects the mitochondrial cysteinome from oxidations in aging

article Full Text OpenAlex

Efficient mitochondrial A-to-G base editors for the generation of mitochondrial disease models

article Full Text OpenAlex

Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting Mitofusin 2

article Full Text OpenAlex

Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque

article Full Text OpenAlex

Aging at the Crossroads of Organ Interactions: Implications for the Heart

review Full Text OpenAlex

Safety Monitoring of Omaveloxolone in Friedreich Ataxia: Results from One Year of Clinical Treatment

article Full Text OpenAlex

Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia

article Full Text OpenAlex

The role of protein lactylation in brain health and disease: current advances and future directions

review Full Text OpenAlex

近5年高被引文献
Copper induces cell death by targeting lipoylated TCA cycle proteins

article Full Text OpenAlex 2986 FWCI459.512

Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants

article Full Text OpenAlex 687 FWCI51.344

Lactate metabolism in human health and disease

review Full Text OpenAlex 684 FWCI31.074

The assembly, regulation and function of the mitochondrial respiratory chain

review Full Text OpenAlex 622 FWCI14.484

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

review Full Text OpenAlex 591 FWCI22.349

Mitochondrial dysfunction in cell senescence and aging

review Full Text OpenAlex 554 FWCI26.243

Distinct fission signatures predict mitochondrial degradation or biogenesis

article Full Text OpenAlex 551 FWCI37.419

Emerging roles of oxidative stress in brain aging and Alzheimer's disease

review Full Text OpenAlex 476 FWCI12.062

Mitochondrial dynamics in health and disease: mechanisms and potential targets

review Full Text OpenAlex 444 FWCI27.756

Mitochondrial fusion and fission: The fine‐tune balance for cellular homeostasis

review Full Text OpenAlex 426 FWCI8.895