This cluster of papers focuses on the epidemiology, diagnosis, management, and pathogenesis of Nonalcoholic Fatty Liver Disease (NAFLD). It covers topics such as liver fibrosis, insulin resistance, hepatic steatosis, metabolic syndrome, nonalcoholic steatohepatitis (NASH), and non-invasive assessment methods. The papers also discuss the association of NAFLD with hepatocellular carcinoma and its impact on public health.