专题:Microtubule and mitosis dynamics

This cluster of papers explores the regulation and function of microtubules in cell division, with a focus on topics such as mitotic checkpoint, molecular motors, aneuploidy, and the role of kinesin proteins and Aurora kinases. It also delves into the implications of chromosomal instability and the potential applications for cancer therapy.
最新文献
Topological Universality of α = 6/5 in Microtubule Lattice Spectra

article Full Text OpenAlex

Molecular basis for the inhibition of de novo DNA methylation by TCL1A

article Full Text OpenAlex

Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C–Mutated Tumors

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CDATA Computational Validation and Mechanics

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Loss of EB2 delays mitotic progression in murine and human neural progenitors

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A molecular and spatial resource defining tubulin isotype organization during corneal development

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Digital Twins of Cell Differentiation Integrating Centrosomal Dynamics

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Ex Vivo Manipulation Strategies for Directed Stem Cell Differentiation

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Pharmacological Control of Cell Fate via Centriole-Associated Determinants

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Adaptor-mediated recruitment of three dyneins to dynactin enhances force generation

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近5年高被引文献
Hallmarks of DNA replication stress

review Full Text OpenAlex 389 FWCI30.6299

Cancer cell plasticity during tumor progression, metastasis and response to therapy

review Full Text OpenAlex 287 FWCI67.044

Principles and dynamics of spindle assembly checkpoint signalling

review Full Text OpenAlex 250 FWCI53.0791

Directed cell migration towards softer environments

article Full Text OpenAlex 230 FWCI24.7569

Mechanisms of microtubule organization in differentiated animal cells

review Full Text OpenAlex 207 FWCI23.1275

Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials

review Full Text OpenAlex 204 FWCI19.9881

P-selectin-targeted nanocarriers induce active crossing of the blood–brain barrier via caveolin-1-dependent transcytosis

article Full Text OpenAlex 189 FWCI29.58

Lactate regulates cell cycle by remodelling the anaphase promoting complex

article Full Text OpenAlex 188 FWCI40.3401

Engineered hydrogels for mechanobiology

article Full Text OpenAlex 185 FWCI20.436

MINFLUX dissects the unimpeded walking of kinesin-1

article Full Text OpenAlex 179 FWCI37.894