专题：Microtubule and mitosis dynamics

This cluster of papers explores the regulation and function of microtubules in cell division, with a focus on topics such as mitotic checkpoint, molecular motors, aneuploidy, and the role of kinesin proteins and Aurora kinases. It also delves into the implications of chromosomal instability and the potential applications for cancer therapy.
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Hallmarks of DNA replication stress

article Full Text OpenAlex 444 FWCI27.4851

Quizartinib plus chemotherapy in newly diagnosed patients with FLT3-internal-tandem-duplication-positive acute myeloid leukaemia (QuANTUM-First): a randomised, double-blind, placebo-controlled, phase 3 trial

article Full Text OpenAlex 390 FWCI70.8842

Cancer cell plasticity during tumor progression, metastasis and response to therapy

article Full Text OpenAlex 325 FWCI37.4394

Principles and dynamics of spindle assembly checkpoint signalling

article Full Text OpenAlex 281 FWCI36.4009

Cyclin-dependent protein kinases and cell cycle regulation in biology and disease

article Full Text OpenAlex 264 FWCI123.3547

Glioblastoma multiforme: insights into pathogenesis, key signaling pathways, and therapeutic strategies

article Full Text OpenAlex 257 FWCI186.6871

Directed cell migration towards softer environments

article Full Text OpenAlex 250 FWCI22.9344

Mechanisms of microtubule organization in differentiated animal cells

article Full Text OpenAlex 229 FWCI21.1226

Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials

article Full Text OpenAlex 218 FWCI17.8344

Lactate regulates cell cycle by remodelling the anaphase promoting complex

article Full Text OpenAlex 213 FWCI27.9653