专题：Microtubule and mitosis dynamics

This cluster of papers explores the regulation and function of microtubules in cell division, with a focus on topics such as mitotic checkpoint, molecular motors, aneuploidy, and the role of kinesin proteins and Aurora kinases. It also delves into the implications of chromosomal instability and the potential applications for cancer therapy.
最新文献
Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction.

article Full Text OpenAlex

Translational Inhibition of Slug by Pdcd4 Contributes to Invasion Inhibition in Colorectal Cancer Cells

article Full Text OpenAlex

Integrative proteogenomics and forward genetics reveals a novel mitotic vulnerability in triple-negative breast cancer

article Full Text OpenAlex

Discovery of unique mitotic mechanisms in Paradiplonema papillatum

article Full Text OpenAlex

Mouse pre-meiotic germline cysts contain fusome-like structure dependent on Dazl that mediates cyst fragmentation and oocyte development

preprint Full Text OpenAlex

Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry

article Full Text OpenAlex

Molecular basis for the activation of Aurora A and Plk1 kinases during mitotic entry

preprint Full Text OpenAlex

Unraveling regulatory feedback mechanisms in adult neurogenesis through mathematical modelling

article Full Text OpenAlex

A decade of discovery: tracing the footmarks of migrasomes, unveiling the footprints of cells.

review Full Text OpenAlex

Cell cycle- and dose-dependent effects on mitochondrial DNA copy number variation following irradiation

article Full Text OpenAlex

近5年高被引文献
Cell cycle control in cancer

review Full Text OpenAlex 1095 FWCI30.955

Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance

review Full Text OpenAlex 534 FWCI16.125

Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy

review Full Text OpenAlex 450 FWCI12.679

Hallmarks of DNA replication stress

review Full Text OpenAlex 269 FWCI9.262

Taxanes in cancer treatment: Activity, chemoresistance and its overcoming

review Full Text OpenAlex 259 FWCI7.01

Regulation of microtubule dynamics, mechanics and function through the growing tip

review Full Text OpenAlex 257 FWCI6.907

Mechanoresponsive metabolism in cancer cell migration and metastasis

review Full Text OpenAlex 249 FWCI6.454

The Influence of Cell Cycle Regulation on Chemotherapy

review Full Text OpenAlex 239 FWCI6.605

Glycogen accumulation and phase separation drives liver tumor initiation

article Full Text OpenAlex 235 FWCI20.442

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

article Full Text OpenAlex 232 FWCI22.969