专题：Ion channel regulation and function

This cluster of papers explores the molecular mechanisms, structure, regulation, and physiological roles of ion channels, with a focus on voltage-gated potassium and calcium channels. It covers topics such as channel structure, membrane proteins, neuronal function, and cell signaling.
最新文献
Design and structural basis of selective 1,4-dihydropyridine inhibitors of the calcium-activated potassium channel K Ca 3.1

article Full Text OpenAlex

Antisense oligonucleotide treatment in a preterm infant with early-onset SCN2A developmental and epileptic encephalopathy

article Full Text OpenAlex

Cryo-EM structures of the small-conductance Ca2+-activated KCa2.2 channel

article Full Text OpenAlex

Highly dynamic and sensitive NEMOer calcium indicators for imaging ER calcium signals in excitable cells

article Full Text OpenAlex

Precision Therapeutics in Lennox–Gastaut Syndrome: Targeting Molecular Pathophysiology in a Developmental and Epileptic Encephalopathy

review Full Text OpenAlex

Co-existence of RBM20 and KCNQ1 gene mutations in a patient with long QT syndrome and dilated cardiomyopathy. “Which came first: Chicken or the egg?”.

article Full Text OpenAlex

Hereditary pseudocholinesterase deficiency in a 4-year-old girl: a case report

article Full Text OpenAlex

Differential state-dependent Nav1.8 inhibition by suzetrigine, LTGO-33, and A-887826

article Full Text OpenAlex

Piezoelectric Nanomaterials for Cancer Therapy: Current Research and Future Perspectives on Glioblastoma

review Full Text OpenAlex

The discovery of the Sph-gated plasma membrane Ca2+ channel in trypanosomatids. A difficult path for a surprising kind of L-Type VGCC

review Full Text OpenAlex

近5年高被引文献
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels

review Full Text OpenAlex 461 FWCI15.644

Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing

article Full Text OpenAlex 332 FWCI40.727

Terahertz Wave Enhances Permeability of the Voltage-Gated Calcium Channel

article Full Text OpenAlex 272 FWCI20.072

Muscarinic Cholinergic Receptor Agonist and Peripheral Antagonist for Schizophrenia

article Full Text OpenAlex 247 FWCI36.486

CaMKII: a central molecular organizer of synaptic plasticity, learning and memory

review Full Text OpenAlex 241 FWCI13.315

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels

article Full Text OpenAlex 231 FWCI17.58

Structure and gating mechanism of the α7 nicotinic acetylcholine receptor

article Full Text OpenAlex 212 FWCI14.86

Structural snapshots of TRPV1 reveal mechanism of polymodal functionality

article Full Text OpenAlex 177 FWCI18.838

Plasma membrane integrity in health and disease: significance and therapeutic potential

review Full Text OpenAlex 174 FWCI4.855

The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction

article Full Text OpenAlex 169 FWCI21.77