专题：Cancer-related molecular mechanisms research

This cluster of papers explores the role of long noncoding RNAs (lncRNAs) in cancer, development, and genome regulation. It covers topics such as the transcriptional landscape, epigenetic regulation, chromatin modification, competing endogenous RNA networks, and the impact of lncRNAs on cell differentiation. The papers also delve into the functional classification and molecular mechanisms of lncRNAs, highlighting their significance in human diseases.
最新文献
BPHL promotes TNBC stemness by resolving R-loops via POLR2A lactylation inhibition and BARD1-mediated ubiquitination

article Full Text OpenAlex

piR-1170 drives brain metastasis and immune evasion via WTAP-mediated m6A methylation reprogramming in triple-negative breast cancer

article Full Text OpenAlex

Regulation of gene expression by alternative polyadenylation in health and disease

review Full Text OpenAlex

Epitranscriptomic control of cancer hallmarks: Functions, mechanisms, and therapeutics of RNA modifications

article Full Text OpenAlex

Nuclear speckle proteins form intrinsic and MALAT1-dependent microphases

article Full Text OpenAlex

Resistance of first-line targeted drugs in hepatocellular carcinoma: the epigenetic regulation mechanisms

article Full Text OpenAlex

Lactate-driven lactylation of HNRNPA1 orchestrates PKM2 splicing and glycolytic reprogramming in bladder cancer

article Full Text OpenAlex

WDR54 enhances NF-κB signaling to promote progression of hepatocellular carcinoma

article Full Text OpenAlex

Molecular crosstalk between miRNAs and lncRNAs in neurodegenerative disease pathways

article Full Text OpenAlex

MicroRNA in cancer therapy: breakthroughs and challenges in early clinical applications

article Full Text OpenAlex

近5年高被引文献
Long non-coding RNAs: definitions, functions, challenges and recommendations

review Full Text OpenAlex 2389 FWCI80.5652

Emerging concepts of miRNA therapeutics: from cells to clinic

review Full Text OpenAlex 974 FWCI29.274

Non-coding RNAs in disease: from mechanisms to therapeutics

review Full Text OpenAlex 901 FWCI30.3923

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer

article Full Text OpenAlex 847 FWCI65.3912

Integrated lncRNA function upon genomic and epigenomic regulation

article Full Text OpenAlex 753 FWCI49.5936

The Hippo signalling pathway and its implications in human health and diseases

article Full Text OpenAlex 751 FWCI59.68

RNA splicing dysregulation and the hallmarks of cancer

review Full Text OpenAlex 575 FWCI14.6474

Specific expression and functions of circular RNAs

article Full Text OpenAlex 473 FWCI27.9379

Targeting non-coding RNAs to overcome cancer therapy resistance

article Full Text OpenAlex 441 FWCI30.9406

Liquid–liquid phase separation drives cellular function and dysfunction in cancer

review Full Text OpenAlex 440 FWCI7.2075