专题:RNA and protein synthesis mechanisms

This cluster of papers focuses on the structure of ribosomes, mechanisms of translation, RNA secondary structure prediction, genetic code expansion, codon usage, tRNA dynamics, and riboswitches. It explores the molecular mechanisms underlying protein synthesis and the role of RNA in regulating translation. The research also delves into the impact of ribosome structure on cellular processes and the potential applications in synthetic biology.
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Evolutionary-scale prediction of atomic-level protein structure with a language model

article Full Text OpenAlex 5303 FWCI484.5873

TBtools-II: A “one for all, all for one” bioinformatics platform for biological big-data mining

article Full Text OpenAlex 3726 FWCI357.2371

Fast and accurate protein structure search with Foldseek

article Full Text OpenAlex 2515 FWCI227.2415

KEGG: biological systems database as a model of the real world

article Full Text OpenAlex 2356 FWCI370.8967

De novo design of protein structure and function with RFdiffusion

article Full Text OpenAlex 2129 FWCI194.1268

SignalP 6.0 predicts all five types of signal peptides using protein language models

article Full Text OpenAlex 2095 FWCI163.6833

AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

article Full Text OpenAlex 2054 FWCI151.803

Robust deep learning–based protein sequence design using ProteinMPNN

article Full Text OpenAlex 1995 FWCI111.056

DeepTMHMM predicts alpha and beta transmembrane proteins using deep neural networks

preprint Full Text OpenAlex 1567 FWCI0

The diversity of splicing modifiers acting on A -1 bulged 5 -splice sites reveals rules for rational drug design

article Full Text OpenAlex 1257 FWCI25.1892