专题:RNA and protein synthesis mechanisms

This cluster of papers focuses on the structure of ribosomes, mechanisms of translation, RNA secondary structure prediction, genetic code expansion, codon usage, tRNA dynamics, and riboswitches. It explores the molecular mechanisms underlying protein synthesis and the role of RNA in regulating translation. The research also delves into the impact of ribosome structure on cellular processes and the potential applications in synthetic biology.
最新文献
2′-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity

article Full Text OpenAlex

Using a GPT-5-driven autonomous lab to optimize the cost and titer of cell-free protein synthesis

article Full Text OpenAlex

A genetically encoded device for transcriptome storage in mammalian cells

article Full Text OpenAlex

Evolution of a fuzzy ribonucleoprotein complex in viral assembly

article Full Text OpenAlex

Generative modeling for RNA splicing prediction and design

article Full Text OpenAlex

Chronic stress antagonizes formation of stress granules

article Full Text OpenAlex

Suboptimal codon pairs trigger ribosome collisions and cellular quality control responses in tRNA modification mutants

article Full Text OpenAlex

The G3BP stress-granule proteins reinforce the integrated stress response translation programme

article Full Text OpenAlex

Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle

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RNA modulates FUS condensate assembly, dynamics, and aggregation through diverse molecular contacts

preprint Full Text OpenAlex

近5年高被引文献
Evolutionary-scale prediction of atomic-level protein structure with a language model

article Full Text OpenAlex 4276 FWCI669.999

TBtools-II: A “one for all, all for one” bioinformatics platform for biological big-data mining

article Full Text OpenAlex 3000 FWCI498.6257

Fast and accurate protein structure search with Foldseek

article Full Text OpenAlex 2107 FWCI326.0004

SignalP 6.0 predicts all five types of signal peptides using protein language models

article Full Text OpenAlex 2093 FWCI179.4489

KEGG: biological systems database as a model of the real world

article Full Text OpenAlex 1733 FWCI419.0044

AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

article Full Text OpenAlex 1680 FWCI162.8589

De novo design of protein structure and function with RFdiffusion

article Full Text OpenAlex 1660 FWCI259.6468

Robust deep learning–based protein sequence design using ProteinMPNN

article Full Text OpenAlex 1598 FWCI123.9077

DeepTMHMM predicts alpha and beta transmembrane proteins using deep neural networks

preprint Full Text OpenAlex 1393 FWCI0

The diversity of splicing modifiers acting on A -1 bulged 5 -splice sites reveals rules for rational drug design

article Full Text OpenAlex 1192 FWCI37.3753