专题:RNA and protein synthesis mechanisms

This cluster of papers focuses on the structure of ribosomes, mechanisms of translation, RNA secondary structure prediction, genetic code expansion, codon usage, tRNA dynamics, and riboswitches. It explores the molecular mechanisms underlying protein synthesis and the role of RNA in regulating translation. The research also delves into the impact of ribosome structure on cellular processes and the potential applications in synthetic biology.
最新文献
TransMA: an explainable multi-modal deep learning model for predicting properties of ionizable lipid nanoparticles in mRNA delivery

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RiNALMo: general-purpose RNA language models can generalize well on structure prediction tasks

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AlphaGenome: advancing regulatory variant effect prediction with a unified DNA sequence model

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Enhanced RNA secondary structure prediction through integrative deep learning and structural context analysis

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Improving AlphaFold2‐ and AlphaFold3‐Based Protein Complex Structure Prediction With MULTICOM4 in CASP16

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Deep learning–guided design of dynamic proteins

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Sequence-based prediction of intermolecular interactions driven by disordered regions

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Cyclic peptide structure prediction and design using AlphaFold2

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Dominant variants in major spliceosome U4 and U5 small nuclear RNA genes cause neurodevelopmental disorders through splicing disruption

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Ultrafast and accurate sequence alignment and clustering of viral genomes

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近5年高被引文献
Accurate prediction of protein structures and interactions using a three-track neural network

article Full Text OpenAlex 4468 FWCI302.772

Sensitive protein alignments at tree-of-life scale using DIAMOND

article Full Text OpenAlex 3089 FWCI173.413

Highly accurate protein structure prediction for the human proteome

article Full Text OpenAlex 2694 FWCI186.255

Evolutionary-scale prediction of atomic-level protein structure with a language model

article Full Text OpenAlex 2646 FWCI401.719

Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences

article Full Text OpenAlex 2187 FWCI135.508

Database resources of the national center for biotechnology information

article Full Text OpenAlex 2186 FWCI132.784

SignalP 6.0 predicts all five types of signal peptides using protein language models

article Full Text OpenAlex 1964 FWCI187.539

TBtools-II: A “one for all, all for one” bioinformatics platform for biological big-data mining

article Full Text OpenAlex 1820 FWCI272.299

Ensembl 2022

article Full Text OpenAlex 1740 FWCI122.743

PLIP 2021: expanding the scope of the protein–ligand interaction profiler to DNA and RNA

article Full Text OpenAlex 1466 FWCI86.629