专题:HIV/AIDS drug development and treatment

This cluster of papers focuses on the efficacy and safety of antiretroviral therapy for HIV infection, including the development of drug resistance, the use of integrase inhibitors and reverse transcriptase inhibitors, and the adverse effects such as hepatotoxicity and renal toxicity. It also explores the use of nucleoside analogues for treating viral diseases.
最新文献
The clinical and economic impact of genotypic resistance testing for people diagnosed with persistent virological non-suppression on tenofovir–lamivudine–dolutegravir in South Africa: a modelling study

article Full Text OpenAlex

Induction-Free Belatacept-Based Immunosuppression in Kidney Transplantation - Early Outcomes

article Full Text OpenAlex

Probability of vertical HIV transmission: a systematic review and meta-regression

review Full Text OpenAlex

Addition of Belatacept to Tacrolimus-Mycophenolate-Prednisone (Quadruple Immunosuppression) in Kidney Transplant Recipients with Donor Specific Antibodies and/or Antibody Mediated Rejection

article Full Text OpenAlex

A Robust and Accurate Filter Paper–Based Dried Plasma Spot Method for Bictegravir Monitoring in HIV Therapy

article Full Text OpenAlex

The flap endonuclease-1 promotes cellular tolerance to a chain-terminating nucleoside analog, alovudine, by counteracting the toxic effect of 53BP1

article Full Text OpenAlex

Bedaquiline, delamanid, linezolid, and clofazimine for rifampicin-resistant and fluoroquinolone-resistant tuberculosis (endTB-Q): an open-label, multicentre, stratified, non-inferiority, randomised, controlled, phase 3 trial.

article Full Text OpenAlex

Lessons for long-acting lenacapavir: catalysing equitable PrEP access in low-income and middle-income countries

review Full Text OpenAlex

Targeting Aurora kinases as essential cell cycle regulators to deliver multi-stage antimalarials against Plasmodium falciparum

preprint Full Text OpenAlex

Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response

article Full Text OpenAlex

近5年高被引文献
Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition

article Full Text OpenAlex 436 FWCI48.717

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults

article Full Text OpenAlex 408 FWCI32.939

2022 update of the drug resistance mutations in HIV-1.

article Full Text OpenAlex 354 FWCI9.512

Cone-shaped HIV-1 capsids are transported through intact nuclear pores

article Full Text OpenAlex 289 FWCI32.478

Pitavastatin to Prevent Cardiovascular Disease in HIV Infection

article Full Text OpenAlex 269 FWCI130.062

Capsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection

article Full Text OpenAlex 220 FWCI24.171

Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses

article Full Text OpenAlex 213 FWCI17.242

2025 update of the drug resistance mutations in HIV-1.

article Full Text OpenAlex 212 FWCI19.629

Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance

review Full Text OpenAlex 191 FWCI5.661

Dihydroartemisinin: A Potential Natural Anticancer Drug

review Full Text OpenAlex 186 FWCI3.236