专题：RNA Research and Splicing

This cluster of papers focuses on the regulation of RNA processing and function, including topics such as alternative splicing, RNA-binding proteins, phase separation, mRNA decay, stress granules, transcriptome analysis, exon junctions, polyadenylation, nonsense-mediated decay, and RNA phase transitions.
最新文献
Mechanistic research and therapeutic prospects of alternative splicing in neurodegenerative diseases

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RNA modifications in gene regulation: Functions and pathways

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RNA-specific local translation is patterned by condensates for multinucleate cell growth

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Nuclear speckles enable processing of RNA from GC-rich isochores

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LUMI-lab: A foundation model-driven autonomous platform enabling discovery of ionizable lipid designs for mRNA delivery

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Subcellular localization as a driver of protein function

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Density transitions in the regulation of transcription

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Centrosomal Memory

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STING controls glycolysis and histone lactylation to drive macrophage metabolic reprogramming in postoperative ileus

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Computational Modeling of Biomolecular Phase Separation: Current Progress and Open Challenges

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近5年高被引文献
YaHS: yet another Hi-C scaffolding tool

article Full Text OpenAlex 2424 FWCI147.0569

Long non-coding RNAs: definitions, functions, challenges and recommendations

article Full Text OpenAlex 2334 FWCI243.4443

The diversity of splicing modifiers acting on A -1 bulged 5 -splice sites reveals rules for rational drug design

article Full Text OpenAlex 1257 FWCI25.1892

Histone post-translational modifications — cause and consequence of genome function

article Full Text OpenAlex 1122 FWCI76.8172

Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

article Full Text OpenAlex 894 FWCI85.874

Integrated lncRNA function upon genomic and epigenomic regulation

article Full Text OpenAlex 777 FWCI54.8774

A conceptual framework for understanding phase separation and addressing open questions and challenges

article Full Text OpenAlex 735 FWCI49.4888

SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

article Full Text OpenAlex 727 FWCI66.4964

The molecular basis for cellular function of intrinsically disordered protein regions

article Full Text OpenAlex 716 FWCI65.3973

Glioblastoma hijacks neuronal mechanisms for brain invasion

article Full Text OpenAlex 633 FWCI58.8778