专题:Virus-based gene therapy research

This cluster of papers covers a wide range of topics related to gene therapy, including the use of viral vectors such as AAV and adenovirus, advancements in oncolytic virus therapy, hematopoietic stem cell gene therapy, immunodeficiency treatments, lentiviral vector applications, transgene expression, and genomic integration. The research reflects the ongoing progress and challenges in the field of gene therapy.
最新文献
Engineering challenges and translational opportunities in emerging gene delivery platforms

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In vivo generation of anti-BCMA CAR-T cells in relapsed or refractory multiple myeloma: a phase 1 study

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In vivo site-specific engineering to reprogram T cells

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Medicinal chemistry strategies targeting viral proteases: From classical design to next-generation therapeutics

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Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors

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Immune evasive DNA donors and recombinases license kilobase-scale writing

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Progress in the development of cytokine armoured CAR T cells

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In vivo base editing gene therapy for heterozygous familial hypercholesterolemia: a phase 1 trial

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LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis

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Oncolytic Viruses in Cancer Immunotherapy: From Molecular Engineering to Clinical Translation

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