专题：Protease and Inhibitor Mechanisms

This cluster of papers explores the multifaceted roles of matrix metalloproteinases (MMPs) in cancer progression, angiogenesis, inflammation regulation, and extracellular matrix remodeling. It also delves into the potential of MMPs as therapeutic targets for cancer therapy and their involvement in various physiological processes such as cell signaling and tissue remodeling.
最新文献
LNG-IUD and breast cancer: Number 2 – 2026

article Full Text OpenAlex

Optimising lipoprotein(a) tests: we are almost there

article Full Text OpenAlex

Plasminogen supplementation reverses fibrinolytic insufficiency in sepsis-induced disseminated intravascular coagulation: a pilot study

article Full Text OpenAlex

Priming the Liver Endocytic Pathway to Accelerate Hepatobiliary Clearance of Nanoparticles

article Full Text OpenAlex

The status of extracellular vesicles as drug carriers and therapeutics

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Sacituzumab Govitecan in Advanced Triple-Negative Breast Cancer

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Proteomic profiling and characterization of extracellular vesicles in an ex vivo takotsubo syndrome model using isolated perfused rat hearts

article Full Text OpenAlex

Prognostic significance of elevated lipoprotein(a) in long-term outcomes after PCI with drug-eluting stents

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Novel serine-derived Phosphinic peptides as potent MMP-13 inhibitors

article Full Text OpenAlex

CD74-Targeted Cathepsin-Inhibitor Antibody–Drug Conjugate Triggers Apoptosis in DLBCL

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近5年高被引文献
Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

review Full Text OpenAlex 841 FWCI198.34

Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology

review Full Text OpenAlex 468 FWCI40.1692

Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction

article Full Text OpenAlex 418 FWCI80.7183

Regulation of Collagen I and Collagen III in Tissue Injury and Regeneration

article Full Text OpenAlex 376 FWCI81.2594

How vascular smooth muscle cell phenotype switching contributes to vascular disease

review Full Text OpenAlex 357 FWCI26.4337

The Role of Matrix Metalloproteinases (MMP-8, MMP-9, MMP-13) in Periodontal and Peri-Implant Pathological Processes

review Full Text OpenAlex 330 FWCI44.8818

Long-term efficacy and safety of inclisiran in patients with high cardiovascular risk and elevated LDL cholesterol (ORION-3): results from the 4-year open-label extension of the ORION-1 trial

article Full Text OpenAlex 295 FWCI89.802

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

article Full Text OpenAlex 262 FWCI56.919

The Interplay between Extracellular Matrix Remodeling and Cancer Therapeutics

review Full Text OpenAlex 256 FWCI66.3034

PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages

article Full Text OpenAlex 251 FWCI20.7098