专题:Protease and Inhibitor Mechanisms

This cluster of papers explores the multifaceted roles of matrix metalloproteinases (MMPs) in cancer progression, angiogenesis, inflammation regulation, and extracellular matrix remodeling. It also delves into the potential of MMPs as therapeutic targets for cancer therapy and their involvement in various physiological processes such as cell signaling and tissue remodeling.
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Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

review Full Text OpenAlex 888 FWCI199.267

Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology

review Full Text OpenAlex 488 FWCI40.1567

Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction

article Full Text OpenAlex 428 FWCI80.9345

Regulation of Collagen I and Collagen III in Tissue Injury and Regeneration

article Full Text OpenAlex 405 FWCI83.481

How vascular smooth muscle cell phenotype switching contributes to vascular disease

review Full Text OpenAlex 388 FWCI26.5071

The Role of Matrix Metalloproteinases (MMP-8, MMP-9, MMP-13) in Periodontal and Peri-Implant Pathological Processes

review Full Text OpenAlex 346 FWCI44.8809

Long-term efficacy and safety of inclisiran in patients with high cardiovascular risk and elevated LDL cholesterol (ORION-3): results from the 4-year open-label extension of the ORION-1 trial

article Full Text OpenAlex 308 FWCI89.0429

The Interplay between Extracellular Matrix Remodeling and Cancer Therapeutics

review Full Text OpenAlex 296 FWCI70.6827

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

article Full Text OpenAlex 279 FWCI55.7265

PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages

article Full Text OpenAlex 261 FWCI20.7064