专题：Protease and Inhibitor Mechanisms

This cluster of papers explores the multifaceted roles of matrix metalloproteinases (MMPs) in cancer progression, angiogenesis, inflammation regulation, and extracellular matrix remodeling. It also delves into the potential of MMPs as therapeutic targets for cancer therapy and their involvement in various physiological processes such as cell signaling and tissue remodeling.
最新文献
[68Ga]Ga-FAPI-46 PET accuracy for cancer imaging with histopathology validation: a single-centre, single-arm, interventional, phase 2 trial

article Full Text OpenAlex

Semaglutide ameliorates retinal vascular permeability destruction in diabetic retinopathy by AnxA2-mediated MMP-9 activation and basement membrane remodeling

article Full Text OpenAlex

Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis

article Full Text OpenAlex

CD142-positive synovial fibroblasts drive meniscus destruction in rheumatoid arthritis

article Full Text OpenAlex

Tethered Exosomes Containing the Matrix Metalloproteinase MT1‐MMP Contribute to Extracellular Matrix Degradation

article Full Text OpenAlex

The Clinical Impact of FAPI PET Imaging: HCC, CCC, CUP & Peritoneal Carcinoma

review Full Text OpenAlex

Probing the molecular mechanisms of naringenin-induced changes in Beta-lactoglobulin structure

article Full Text OpenAlex

The Value of FAPI PET/CT in Cholangiocarcinoma and Pancreatic Cancer: An Update

review Full Text OpenAlex

Hyaluronidase: structure, mechanism of action, diseases and therapeutic targets

review Full Text OpenAlex

GPLD1 Attenuates Heart Failure via Dual Membrane Localization to Inhibit uPAR

article Full Text OpenAlex

近5年高被引文献
A guide to the composition and functions of the extracellular matrix

review Full Text OpenAlex 740 FWCI19.449

Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

review Full Text OpenAlex 483 FWCI33.667

Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis

review Full Text OpenAlex 332 FWCI8.279

Matrix Metalloproteinases Shape the Tumor Microenvironment in Cancer Progression

review Full Text OpenAlex 332 FWCI8.347

Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology

review Full Text OpenAlex 330 FWCI13.6

Inflammation during the life cycle of the atherosclerotic plaque

review Full Text OpenAlex 324 FWCI7.151

Hyaluronic Acid: A Key Ingredient in the Therapy of Inflammation

review Full Text OpenAlex 295 FWCI6.907

Multifunctional intracellular matrix metalloproteinases: implications in disease

review Full Text OpenAlex 291 FWCI7.772

Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

article Full Text OpenAlex 245 FWCI29.19

Regulation of Collagen I and Collagen III in Tissue Injury and Regeneration

article Full Text OpenAlex 234 FWCI77.407