专题:Gene Regulatory Network Analysis

This cluster of papers focuses on the stochastic behavior and regulation of gene networks, exploring topics such as stochastic gene expression, synthetic biology, cellular noise, network inference, genetic circuits, biochemical modeling, cell signaling dynamics, and single-cell analysis. The research delves into understanding the inherent stochasticity in gene regulatory networks and its implications for cellular functions.
最新文献
Tangermeme: a toolkit for understanding cis-regulatory logic using deep learning models

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The STRING database in 2025: protein networks with directionality of regulation

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Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

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stVCR: spatiotemporal dynamics of single cells

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Bringing the genetically minimal cell to life on a computer in 4D

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Modelling drug-induced cellular perturbation responses with a biologically informed dual-branch transformer

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A genetically encoded device for transcriptome storage in mammalian cells

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Ultra-high-throughput mapping of genetic design space

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Pertpy: an end-to-end framework for perturbation analysis

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Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

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近5年高被引文献
CellChat for systematic analysis of cell–cell communication from single-cell transcriptomics

article Full Text OpenAlex 1415 FWCI161.6529

scGPT: toward building a foundation model for single-cell multi-omics using generative AI

article Full Text OpenAlex 1396 FWCI156.1576

Cell2location maps fine-grained cell types in spatial transcriptomics

article Full Text OpenAlex 1263 FWCI62.3655

Transfer learning enables predictions in network biology

article Full Text OpenAlex 1176 FWCI87.2131

decoupleR: ensemble of computational methods to infer biological activities from omics data

article Full Text OpenAlex 1080 FWCI46.5672

CellRank for directed single-cell fate mapping

article Full Text OpenAlex 775 FWCI40.4962

SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

article Full Text OpenAlex 768 FWCI56.4243

Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

article Full Text OpenAlex 739 FWCI48.1636

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

article Full Text OpenAlex 718 FWCI34.5636

The STRING database in 2025: protein networks with directionality of regulation

article Full Text OpenAlex 668 FWCI77.5394