专题：Cancer, Hypoxia, and Metabolism

This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression.
最新文献
Multi-omics profiling of cachexia-targeted tissues reveals a spatio-temporally coordinated response to cancer

article Full Text OpenAlex

Metabolic reprogramming signature predicts immunotherapy efficacy in lung adenocarcinoma: Targeting SLC25A1 to overcome immune resistance

article Full Text OpenAlex

Inhibiting macrophage-derived lactate transport restores cGAS–STING signalling and enhances antitumour immunity in glioblastoma

article Full Text OpenAlex

Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity

article Full Text OpenAlex

Tumor microenvironment in glioblastoma: The central role of the hypoxic–necrotic core

review Full Text OpenAlex

β‐Hydroxybutyrate Acts as an Exercise Mimetic to Protect the Aging Liver

article Full Text OpenAlex

Automated Synthesis of NET-Targeted PET Tracers [ 18 F]4F-mHPG and [ 18 F]3F-pHPG through Photocatalyzed 18 F-Deoxyfluorination

article Full Text OpenAlex

Recent progress in serine metabolism reprogramming in tumors and strategies for serine deprivation

review Full Text OpenAlex

Dissecting neuroblastoma heterogeneity through single-cell multi-omics: insights into development, immunity, and therapeutic resistance

article Full Text OpenAlex

Targeting of HIF2-driven cachexia in kidney cancer

article Full Text OpenAlex

近5年高被引文献
The role of ROS in tumour development and progression

review Full Text OpenAlex 1434 FWCI129.2343

The hallmarks of cancer metabolism: Still emerging

review Full Text OpenAlex 1272 FWCI116.399

Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions

review Full Text OpenAlex 1194 FWCI290.1816

Lactate metabolism in human health and disease

review Full Text OpenAlex 1188 FWCI104.2464

Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis

article Full Text OpenAlex 1048 FWCI286.3356

Small molecule metabolites: discovery of biomarkers and therapeutic targets

review Full Text OpenAlex 712 FWCI111.9927

Metabolic programming and immune suppression in the tumor microenvironment

review Full Text OpenAlex 523 FWCI127.083

Hypoxia-inducible factors: cancer progression and clinical translation

review Full Text OpenAlex 515 FWCI47.1886

The role of lipids in cancer progression and metastasis

review Full Text OpenAlex 500 FWCI44.9099

Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma

article Full Text OpenAlex 490 FWCI120.8431