专题：Cancer, Hypoxia, and Metabolism

This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression.
最新文献
Multi-omics profiling of cachexia-targeted tissues reveals a spatio-temporally coordinated response to cancer

article Full Text OpenAlex

Inhibiting macrophage-derived lactate transport restores cGAS–STING signalling and enhances antitumour immunity in glioblastoma

article Full Text OpenAlex

NDRG1–HIF1α interaction in hypoxic signaling for pulmonary hypertension

article Full Text OpenAlex

Microenvironmental regulation and remodeling of breast cancer angiogenesis: from basic mechanisms to clinical therapeutic implications

review Full Text OpenAlex

Synergistic dual oncogenic role of CKS2 and ACAT2: Enhanced regulatory coherence and biomarker potential in adrenocortical carcinoma

article Full Text OpenAlex

Conserved hydrophilic checkpoints tune FocA-mediated formate:H+ symport

article Full Text OpenAlex

Targeting mitochondrial structure and dynamics for therapeutic intervention in cancer

article Full Text OpenAlex

PFKFB3 as a multifaceted driver and therapeutic target in castration-resistant prostate cancer

article Full Text OpenAlex

Glutaminase inhibitor CB-839 causes metabolic adjustments in colorectal cancer cells

article Full Text OpenAlex

EGFR gene amplification in IDH-wildtype glioblastomas: an integrative bioinformatic and histopathological analysis using immunohistochemistry and fluorescence in situ hybridization

article Full Text OpenAlex

近5年高被引文献
The role of ROS in tumour development and progression

review Full Text OpenAlex 1362 FWCI184.90086159

The hallmarks of cancer metabolism: Still emerging

review Full Text OpenAlex 1210 FWCI166.54673195

Lactate metabolism in human health and disease

review Full Text OpenAlex 1100 FWCI148.60047185

Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions

review Full Text OpenAlex 1086 FWCI242.17255456

Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis

article Full Text OpenAlex 1005 FWCI353.23160989

Small molecule metabolites: discovery of biomarkers and therapeutic targets

review Full Text OpenAlex 662 FWCI123.28515067

Hypoxia-inducible factors: cancer progression and clinical translation

review Full Text OpenAlex 491 FWCI67.29847536

Metabolic programming and immune suppression in the tumor microenvironment

review Full Text OpenAlex 477 FWCI106.17307769

The role of lipids in cancer progression and metastasis

review Full Text OpenAlex 467 FWCI64.30743201

Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma

article Full Text OpenAlex 449 FWCI101.49879125