专题:Cancer, Hypoxia, and Metabolism

This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression.
最新文献
Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis

article Full Text OpenAlex

Metabolic checkpoints in rheumatoid arthritis

review Full Text OpenAlex

Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells

article Full Text OpenAlex

The Tumor Microbiome Reacts to Hypoxia and Can Influence Response to Radiation Treatment in Colorectal Cancer

article Full Text OpenAlex

ASS1 enhances anoikis resistance via AMPK/CPT1A-mediated fatty acid metabolism in ovarian cancer

article Full Text OpenAlex

Asparagine Dependency Is a Targetable Metabolic Vulnerability in TP53 -Altered Castration-Resistant Prostate Cancer

article Full Text OpenAlex

ZDHHC1 downregulates LIPG and inhibits colorectal cancer growth via IGF2BP1 Palmitoylation

article Full Text OpenAlex

All organic nanomedicine for PDT–PTT combination therapy of cancer cells in hypoxia

article Full Text OpenAlex

The role of cancer-associated fibroblasts in the invasion and metastasis of colorectal cancer

review Full Text OpenAlex

A brave new framework for glioma drug development

review Full Text OpenAlex

近5年高被引文献
Cancer metabolism: looking forward

review Full Text OpenAlex 1642 FWCI137.19635666

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

article Full Text OpenAlex 1547 FWCI214.19349536

The role of ROS in tumour development and progression

review Full Text OpenAlex 1325 FWCI180.95812263

The hallmarks of cancer metabolism: Still emerging

review Full Text OpenAlex 1163 FWCI162.46803647

The cancer metabolic reprogramming and immune response

review Full Text OpenAlex 1116 FWCI88.08326401

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

article Full Text OpenAlex 1080 FWCI87.01574891

Lactate metabolism in human health and disease

review Full Text OpenAlex 1051 FWCI143.57008076

Targeting cancer metabolism in the era of precision oncology

review Full Text OpenAlex 1041 FWCI83.49225752

Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions

review Full Text OpenAlex 1000 FWCI223.03023867

Photodynamic Therapy Review: Principles, Photosensitizers, Applications, and Future Directions

review Full Text OpenAlex 988 FWCI115.49822665