专题：Ion Transport and Channel Regulation

This cluster of papers explores the molecular mechanisms, physiological roles, and pathophysiological implications of aquaporins, a family of water channel proteins involved in ion transport across cell membranes. The research covers various aspects such as brain edema, kidney function, regulation, and the role of aquaporins in disease.
最新文献
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes

article Full Text OpenAlex

Clinical and Genetic Characteristics of Two Cases With Developmental and Epileptic Encephalopathy 93 Caused by Novel ATP6V1A Mutations and Literature Review

review Full Text OpenAlex

Pathological and functional significance of aging mouse kidneys: clinical implications to reduce the risk of hyper- or hypokalemia in the elderly

article Full Text OpenAlex

Fahr’s syndrome as the initial imaging characteristics of MELAS syndrome with a possible seizure activity and cardiac arrest: a case report

article Full Text OpenAlex

Nephron specific ATP6AP2 knockout increases urinary excretion of fatty acids and decreases renal cortical megalin expression

article Full Text OpenAlex

Desmopressin dosing in children using real-world data and pharmacokinetic/pharmacodynamic model simulations

article Full Text OpenAlex

Gene therapy for targeting a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death

preprint Full Text OpenAlex

Mice lacking acid-sensing ion channel 2 in the medial prefrontal cortex exhibit social dominance

article Full Text OpenAlex

High chloride induces aldosterone resistance in the distal nephron

article Full Text OpenAlex

Mutagenesis of the Peptide Inhibitor of ASIC3 Channel Introduces Binding to Thumb Domain of ASIC1a but Reduces Analgesic Activity

article Full Text OpenAlex

近5年高被引文献
Chronic kidney disease

review Full Text OpenAlex 1202 FWCI156.04239769

Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension

article Full Text OpenAlex 290 FWCI61.08178225

Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial

article Full Text OpenAlex 245 FWCI53.57311206

Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis

article Full Text OpenAlex 218 FWCI15.60518836

Molecular mechanisms of brain water transport

review Full Text OpenAlex 201 FWCI15.60518836

Mineralocorticoid receptor antagonists in diabetic kidney disease — mechanistic and therapeutic effects

review Full Text OpenAlex 195 FWCI27.85936526

Hyperkalemia Risk with Finerenone: Results from the FIDELIO-DKD Trial

article Full Text OpenAlex 189 FWCI23.52414111

How Many Cell Types Are in the Kidney and What Do They Do?

review Full Text OpenAlex 182 FWCI11.41129399

WNK kinases sense molecular crowding and rescue cell volume via phase separation

article Full Text OpenAlex 160 FWCI28.53992265

Albuminuria-Lowering Effect of Dapagliflozin, Eplerenone, and Their Combination in Patients with Chronic Kidney Disease: A Randomized Crossover Clinical Trial

article Full Text OpenAlex 153 FWCI32.22590581