专题：RNA Interference and Gene Delivery

This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.
最新文献
The Biology of Endosomal Escape: Strategies for Enhanced Delivery of Therapeutics

article Full Text OpenAlex

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

article Full Text OpenAlex

MiRNA-based drugs: challenges and delivery strategies

article Full Text OpenAlex

Advances in Lipid-Polymer Hybrid Nanoparticles: Design Strategies, Functionalization, Oncological and Non-Oncological Clinical Prospects

article Full Text OpenAlex

Endosomal Escape of Lipid Nanoparticles: A Perspective on the Literature Data

article Full Text OpenAlex

Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine

article Full Text OpenAlex

A skin-permeable polymer for non-invasive transdermal insulin delivery

article Full Text OpenAlex

Deep generative optimization of mRNA codon sequences for enhanced mRNA translation and therapeutic efficacy

article Full Text OpenAlex

Sub-15 nm Nanoparticles for Drug Delivery: Emerging Frontiers and Therapeutic Potential

review Full Text OpenAlex

Progress in peptide and protein therapeutics: Challenges and strategies

article Full Text OpenAlex

近5年高被引文献
Liposomes: structure, composition, types, and clinical applications

review Full Text OpenAlex 1345 FWCI94.6084

Drug delivery systems for RNA therapeutics

review Full Text OpenAlex 1190 FWCI94.1932

The role of lipid components in lipid nanoparticles for vaccines and gene therapy

review Full Text OpenAlex 1057 FWCI79.6358

Emerging concepts of miRNA therapeutics: from cells to clinic

review Full Text OpenAlex 922 FWCI80.8041

The role of BCL-2 family proteins in regulating apoptosis and cancer therapy

review Full Text OpenAlex 871 FWCI64.9048

Polymeric Nanoparticles for Drug Delivery

review Full Text OpenAlex 851 FWCI136.8753

Targeting drugs to tumours using cell membrane-coated nanoparticles

review Full Text OpenAlex 843 FWCI60.7341

Vaccine adjuvants: mechanisms and platforms

review Full Text OpenAlex 801 FWCI126.6863

The clinical progress of mRNA vaccines and immunotherapies

review Full Text OpenAlex 751 FWCI59.1943

Chemistry, structure and function of approved oligonucleotide therapeutics

review Full Text OpenAlex 730 FWCI108.9117