专题：RNA Interference and Gene Delivery

This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.
最新文献
Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors

article Full Text OpenAlex

MiRNA-based drugs: challenges and delivery strategies

article Full Text OpenAlex

Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine

article Full Text OpenAlex

Progress in peptide and protein therapeutics: Challenges and strategies

article Full Text OpenAlex

Review of Chitosan-Coated Nanoscale Liposomes for Enhanced Drug Delivery

article Full Text OpenAlex

The evolution of nanomedicine: The rise of next-generation nanomaterials in cancer nanomedicine

review Full Text OpenAlex

Advances in Cancer Treatment Through Nanotheranostics and Emerging Therapies

article Full Text OpenAlex

Visualizing the chronicle of multiple cell fates using a near-IR dual-RNA/DNA–targeting probe

article Full Text OpenAlex

Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models

article Full Text OpenAlex

Exosome-Based Drug Delivery: A Next-Generation Platform for Cancer, Infection, Neurological and Immunological Diseases, Gene Therapy and Regenerative Medicine

review Full Text OpenAlex

近5年高被引文献
Liposomes: structure, composition, types, and clinical applications

review Full Text OpenAlex 1281 FWCI94.2002

Drug delivery systems for RNA therapeutics

review Full Text OpenAlex 1148 FWCI94.3035

The role of lipid components in lipid nanoparticles for vaccines and gene therapy

review Full Text OpenAlex 992 FWCI79.8019

Emerging concepts of miRNA therapeutics: from cells to clinic

review Full Text OpenAlex 893 FWCI79.6605

The role of BCL-2 family proteins in regulating apoptosis and cancer therapy

review Full Text OpenAlex 820 FWCI64.9041

Targeting drugs to tumours using cell membrane-coated nanoparticles

review Full Text OpenAlex 805 FWCI60.3557

Polymeric Nanoparticles for Drug Delivery

review Full Text OpenAlex 750 FWCI135.4324

Vaccine adjuvants: mechanisms and platforms

review Full Text OpenAlex 730 FWCI122.07

The clinical progress of mRNA vaccines and immunotherapies

review Full Text OpenAlex 718 FWCI59.2219

Chemistry, structure and function of approved oligonucleotide therapeutics

review Full Text OpenAlex 689 FWCI108.9277