专题：RNA Interference and Gene Delivery

This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.
最新文献
LUMI-lab: A foundation model-driven autonomous platform enabling discovery of ionizable lipid designs for mRNA delivery

article Full Text OpenAlex

The Biology of Endosomal Escape: Strategies for Enhanced Delivery of Therapeutics

review Full Text OpenAlex

MiRNA-based drugs: challenges and delivery strategies

review Full Text OpenAlex

Advances in Lipid-Polymer Hybrid Nanoparticles: Design Strategies, Functionalization, Oncological and Non-Oncological Clinical Prospects

review Full Text OpenAlex

Endosomal Escape of Lipid Nanoparticles: A Perspective on the Literature Data

review Full Text OpenAlex

Antimicrobial Peptides: Current Status, Mechanisms of Action, and Strategies to Overcome Therapeutic Limitations

review Full Text OpenAlex

Advances in RNA-based therapeutics: current breakthroughs, clinical translation, and future perspectives

review Full Text OpenAlex

Exosome-Based Drug Delivery: A Next-Generation Platform for Cancer, Infection, Neurological and Immunological Diseases, Gene Therapy and Regenerative Medicine

review Full Text OpenAlex

In vivo CAR T cell generation to treat cancer and autoimmune disease

article Full Text OpenAlex

Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies

review Full Text OpenAlex

近5年高被引文献
Liposomes: structure, composition, types, and clinical applications

article Full Text OpenAlex 1552 FWCI63.3075

CAR T cells produced in vivo to treat cardiac injury

article Full Text OpenAlex 1385 FWCI92.4298

Drug delivery systems for RNA therapeutics

review Full Text OpenAlex 1335 FWCI22.3824

The role of lipid components in lipid nanoparticles for vaccines and gene therapy

review Full Text OpenAlex 1193 FWCI18.8187

Emerging concepts of miRNA therapeutics: from cells to clinic

review Full Text OpenAlex 973 FWCI29.274

Nanomedicine in cancer therapy

article Full Text OpenAlex 888 FWCI48.9177

Adeno-associated virus as a delivery vector for gene therapy of human diseases

article Full Text OpenAlex 847 FWCI201.5193

Chemistry, structure and function of approved oligonucleotide therapeutics

article Full Text OpenAlex 835 FWCI62.1335

The clinical progress of mRNA vaccines and immunotherapies

article Full Text OpenAlex 820 FWCI45.6019

mRNA-based therapeutics: powerful and versatile tools to combat diseases

article Full Text OpenAlex 777 FWCI41.7428