专题：RNA Interference and Gene Delivery

This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.
最新文献
From cell-SELEX to tissue-SELEX for targeted drug delivery and aptamer nanomedicine

review Full Text OpenAlex

NANOSPRESSO: toward personalized, locally produced nucleic acid nanomedicines

article Full Text OpenAlex

Methods and Challenges in Purifying Drug‐Loaded Extracellular Vesicles

review Full Text OpenAlex

Next-Generation Nucleic Acid Delivery: A Review of Nanobiosystem Design and Applications

review Full Text OpenAlex

Poly(carboxybetaine) lipids enhance mRNA therapeutics efficacy and reduce their immunogenicity

article Full Text OpenAlex

Nanotechnology in leukemia therapy: revolutionizing targeted drug delivery and immune modulation

review Full Text OpenAlex

Engineered exosomes: a promising drug delivery platform with therapeutic potential

review Full Text OpenAlex

Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

article Full Text OpenAlex

Ocular drug delivery systems based on nanotechnology: a comprehensive review for the treatment of eye diseases

review Full Text OpenAlex

Exosome-powered neuropharmaceutics: unlocking the blood-brain barrier for next-gen therapies

review Full Text OpenAlex

近5年高被引文献
Lipid nanoparticles for mRNA delivery

review Full Text OpenAlex 2532 FWCI56.857

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

article Full Text OpenAlex 2103 FWCI314.04

Lipid Nanoparticles─From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement

review Full Text OpenAlex 1550 FWCI34.753

The exosome journey: from biogenesis to uptake and intracellular signalling

review Full Text OpenAlex 1318 FWCI30.244

Noncoding RNA therapeutics — challenges and potential solutions

review Full Text OpenAlex 1226 FWCI35.483

mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

review Full Text OpenAlex 1154 FWCI28.019

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

review Full Text OpenAlex 1107 FWCI26.145

Engineering exosomes for targeted drug delivery

review Full Text OpenAlex 1103 FWCI25.56

Viral vector platforms within the gene therapy landscape

review Full Text OpenAlex 1044 FWCI36.738

The evolution of commercial drug delivery technologies

review Full Text OpenAlex 1042 FWCI25.237