专题：RNA Interference and Gene Delivery

This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.
最新文献
Self-assembling protein nanoparticles for cytosolic delivery of nucleic acids and proteins

article Full Text OpenAlex

Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors

article Full Text OpenAlex

Engineered Exosomes as Smart Drug Carriers: Overcoming Biological Barriers in CNS and Cancer Therapy

article Full Text OpenAlex

MicroRNA in cancer therapy: breakthroughs and challenges in early clinical applications

review Full Text OpenAlex

Ionizable lipid nanoparticles of mRNA vaccines elicit NF-κB and IRF responses through toll-like receptor 4

article Full Text OpenAlex

Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines

article Full Text OpenAlex

A new era of cancer immunotherapy: vaccines and miRNAs

review Full Text OpenAlex

RNAi applications towards environmentally sustainable food security

article Full Text OpenAlex

Liposomes as Immunotherapeutic Carriers: A Game-Changer in Cancer Therapy

article Full Text OpenAlex

The Application of Dendritic Cells Vaccines in Tumor Therapy and Their Combination with Biomimetic Nanoparticles

review Full Text OpenAlex

近5年高被引文献
Lipid nanoparticles for mRNA delivery

review Full Text OpenAlex 2326 FWCI56.854

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

article Full Text OpenAlex 2049 FWCI314.061

Lipid Nanoparticles─From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement

review Full Text OpenAlex 1471 FWCI34.733

The exosome journey: from biogenesis to uptake and intracellular signalling

review Full Text OpenAlex 1267 FWCI30.257

Noncoding RNA therapeutics — challenges and potential solutions

review Full Text OpenAlex 1197 FWCI35.532

mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

review Full Text OpenAlex 1085 FWCI27.973

Engineering exosomes for targeted drug delivery

review Full Text OpenAlex 1047 FWCI25.545

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

review Full Text OpenAlex 1032 FWCI26.13

The evolution of commercial drug delivery technologies

review Full Text OpenAlex 1023 FWCI25.248

Viral vector platforms within the gene therapy landscape

review Full Text OpenAlex 1019 FWCI36.728