专题：CRISPR and Genetic Engineering

This cluster of papers focuses on the use of CRISPR-Cas systems for genome engineering, RNA-guided gene editing, and bacterial immunity. It covers topics such as Cas9 nucleases, off-target effects, multiplex genome editing, and genetic screening using CRISPR technology.
最新文献
Engineering the plant microbiome: synthetic community approaches to enhance crop protection

article Full Text OpenAlex

SPARK-seq: A high-throughput platform for aptamer discovery and kinetic profiling

article Full Text OpenAlex

Scarless circular mRNA-based CAR-T cell therapy elicits superior antitumor efficacy

article Full Text OpenAlex

Gene-drive-capable mosquitoes suppress patient-derived malaria in Tanzania

article Full Text OpenAlex

In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles

article Full Text OpenAlex

One-Pot CRISPR-Based Isothermal Amplification for Nucleic Acid Detection: A Comparative Review of Different Strategies

review Full Text OpenAlex

Ensembl 2026

article Full Text OpenAlex

Epigenetic editing: from concept to clinic

article Full Text OpenAlex

A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release

article Full Text OpenAlex

Cas12a-assisted split crRNA complex for analysis and detection of diverse entities

article Full Text OpenAlex

近5年高被引文献
Single‐cell RNA sequencing technologies and applications: A brief overview

review Full Text OpenAlex 1226 FWCI97.4867

The conserved domain database in 2023

article Full Text OpenAlex 1127 FWCI88.8216

Histone post-translational modifications — cause and consequence of genome function

review Full Text OpenAlex 1044 FWCI85.1817

CRISPR technology: A decade of genome editing is only the beginning

review Full Text OpenAlex 987 FWCI145.7579

Automated assembly scaffolding using RagTag elevates a new tomato system for high-throughput genome editing

article Full Text OpenAlex 903 FWCI70.3641

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

article Full Text OpenAlex 828 FWCI156.9802

Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 827 FWCI56.594

Ensembl 2024

article Full Text OpenAlex 704 FWCI104.1128

Drugging p53 in cancer: one protein, many targets

review Full Text OpenAlex 703 FWCI67.7367

CRISPR/Cas9 therapeutics: progress and prospects

review Full Text OpenAlex 635 FWCI93.9755