专题：CRISPR and Genetic Engineering

This cluster of papers focuses on the use of CRISPR-Cas systems for genome engineering, RNA-guided gene editing, and bacterial immunity. It covers topics such as Cas9 nucleases, off-target effects, multiplex genome editing, and genetic screening using CRISPR technology.
最新文献
NANOSPRESSO: toward personalized, locally produced nucleic acid nanomedicines

article Full Text OpenAlex

A mitochondrial disease model is generated and corrected using engineered base editors in rat zygotes

article Full Text OpenAlex

Efficient mitochondrial A-to-G base editors for the generation of mitochondrial disease models

article Full Text OpenAlex

Stem cell therapy: a revolutionary cure or a pandora's box

review Full Text OpenAlex

A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types

article Full Text OpenAlex

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

article Full Text OpenAlex

Modulation of the PI3K/Akt signaling pathway by resveratrol in cancer: molecular mechanisms and therapeutic opportunity

review Full Text OpenAlex

Gag proteins encoded by endogenous retroviruses are required for zebrafish development

article Full Text OpenAlex

Advances in CRISPR/Cas13a-based biosensors for non-coding RNA detection

review Full Text OpenAlex

Rewriting regulatory DNA to dissect and reprogram gene expression

article Full Text OpenAlex

近5年高被引文献
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

article Full Text OpenAlex 1234 FWCI85.496

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

article Full Text OpenAlex 1111 FWCI70.234

The evolution of commercial drug delivery technologies

review Full Text OpenAlex 1006 FWCI25.194

CRISPR-based diagnostics

review Full Text OpenAlex 865 FWCI21.682

Nextclade: clade assignment, mutation calling and quality control for viral genomes

article Full Text OpenAlex 785 FWCI55.234

Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022

article Full Text OpenAlex 751 FWCI47.175

Single‐cell RNA sequencing technologies and applications: A brief overview

review Full Text OpenAlex 748 FWCI27.038

Genome engineering for crop improvement and future agriculture

review Full Text OpenAlex 693 FWCI17.556

Histone post-translational modifications — cause and consequence of genome function

review Full Text OpenAlex 646 FWCI24.428

CRISPR technology: A decade of genome editing is only the beginning

review Full Text OpenAlex 645 FWCI40.259