专题：CRISPR and Genetic Engineering

This cluster of papers focuses on the use of CRISPR-Cas systems for genome engineering, RNA-guided gene editing, and bacterial immunity. It covers topics such as Cas9 nucleases, off-target effects, multiplex genome editing, and genetic screening using CRISPR technology.
最新文献
Development of a split-toxin CRISPR screening platform to systematically identify regulators of human myoblast fusion

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Genome engineering for conservation might be a game changer but only with the incorporation of Indigenous voices

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SPARK-seq: A high-throughput platform for aptamer discovery and kinetic profiling

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Comprehensive Mapping of the Virus and Host Factors that Guide the Paths of HIV-1 Escape from a Therapeutic

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A novel multiplex RPA/CRISPR-Cas12a integrated biosensor for on-site detection of high-risk HPV genotypes

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CAR T cells for multiple sclerosis: Engineering T cells to disrupt chronic B cell–driven neuroinflammation

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Using Disease Models for Mechanistic Studies: Special Focus on Gene Editing

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Genome editing in horticultural crops: augmenting trait development and stress resilience

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A multistep platform identifies spleen-tropic lipid nanoparticles for in vivo T cell–targeted delivery of gene-editing proteins

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Aberrant X chromosome dosage compensation causes hybrid male inviability in Caenorhabditis

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近5年高被引文献
Single‐cell RNA sequencing technologies and applications: A brief overview

review Full Text OpenAlex 1091 FWCI137.34518031

The conserved domain database in 2023

article Full Text OpenAlex 984 FWCI124.79212619

Histone post-translational modifications — cause and consequence of genome function

review Full Text OpenAlex 950 FWCI120.85391314

CRISPR technology: A decade of genome editing is only the beginning

review Full Text OpenAlex 889 FWCI165.24666279

Automated assembly scaffolding using RagTag elevates a new tomato system for high-throughput genome editing

article Full Text OpenAlex 799 FWCI99.19374133

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

article Full Text OpenAlex 785 FWCI221.82096766

Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 768 FWCI79.62574521

Drugging p53 in cancer: one protein, many targets

review Full Text OpenAlex 641 FWCI95.78429898

Ensembl 2024

article Full Text OpenAlex 600 FWCI111.77358539

CRISPR/Cas9 therapeutics: progress and prospects

review Full Text OpenAlex 572 FWCI106.57481398