专题：CRISPR and Genetic Engineering

This cluster of papers focuses on the use of CRISPR-Cas systems for genome engineering, RNA-guided gene editing, and bacterial immunity. It covers topics such as Cas9 nucleases, off-target effects, multiplex genome editing, and genetic screening using CRISPR technology.
最新文献
NANOSPRESSO: toward personalized, locally produced nucleic acid nanomedicines

article Full Text OpenAlex

LbuCas13a directly targets DNA and elicits strong trans-cleavage activity

article Full Text OpenAlex

Base editing of trinucleotide repeats that cause Huntington’s disease and Friedreich’s ataxia reduces somatic repeat expansions in patient cells and in mice

article Full Text OpenAlex

A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types

article Full Text OpenAlex

Admixture’s impact on Brazilian population evolution and health

article Full Text OpenAlex

Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase

article Full Text OpenAlex

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

article Full Text OpenAlex

Spatially Resolved Panoramic in vivo CRISPR Screen via Perturb-DBiT

preprint Full Text OpenAlex

RNA interference in Agriculture: Basic Science to Applications

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Efficient and selective energy transfer photoenzymes powered by visible light

article Full Text OpenAlex

近5年高被引文献
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

article Full Text OpenAlex 1281 FWCI85.617

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

article Full Text OpenAlex 1119 FWCI70.349

The evolution of commercial drug delivery technologies

review Full Text OpenAlex 1042 FWCI25.237

CRISPR-based diagnostics

review Full Text OpenAlex 925 FWCI21.695

Nextclade: clade assignment, mutation calling and quality control for viral genomes

article Full Text OpenAlex 841 FWCI55.262

Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022

article Full Text OpenAlex 790 FWCI47.167

Single‐cell RNA sequencing technologies and applications: A brief overview

review Full Text OpenAlex 788 FWCI27.158

Genome engineering for crop improvement and future agriculture

review Full Text OpenAlex 737 FWCI17.596

Histone post-translational modifications — cause and consequence of genome function

review Full Text OpenAlex 716 FWCI24.816

CRISPR technology: A decade of genome editing is only the beginning

review Full Text OpenAlex 706 FWCI38.665