专题：Wnt/β-catenin signaling in development and cancer

This cluster of papers focuses on the Wnt signaling pathway and its role in development, stem cells, cancer, and disease. It covers components, mechanisms, diseases, therapeutic modalities, and the impact of Wnt signaling on osteoblast and chondrocyte differentiation.
最新文献
Retraction: Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction

article Full Text OpenAlex

STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency

article Full Text OpenAlex

The mechanotransduction-immune axis in organ fibrosis: dual regulatory mechanisms and translational therapeutic perspectives

article Full Text OpenAlex

A collagenous extracellular matrix regulates germline gene expression in the sea star embryo

article Full Text OpenAlex

From Adhesion to Invasion: Integrins, Focal Adhesion Signaling, and Actin Binding Proteins in Cervical Cancer Progression—A Scoping Review

review Full Text OpenAlex

Polarity protein Par6: Unraveling its mechanisms in tumor development and research advances

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The dual role of glycogen synthase kinase-3 beta (GSK3β) in neurodegenerative pathologies: interplay between autophagy and disease progression

review Full Text OpenAlex

Targeting GSK-3β to Modulate the Wnt Pathway: A Promising Neuroprotective Strategy for Alzheimer’s Disease

article Full Text OpenAlex

Cancer-associated fibroblasts enhance colorectal cancer lymphatic metastasis via CLEC11A/LGR5-mediated WNT pathway activation

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β‐Elemene Suppresses Proliferation, Migration, and Stemness in Triple‐Negative Breast Cancer by Inhibiting SIX‐1

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近5年高被引文献
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

review Full Text OpenAlex 1977 FWCI239.36951227

Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

review Full Text OpenAlex 740 FWCI91.93266101

The Hippo signalling pathway and its implications in human health and diseases

review Full Text OpenAlex 573 FWCI93.37852092

Ischemia-reperfusion injury: molecular mechanisms and therapeutic targets

article Full Text OpenAlex 446 FWCI214.19026241

The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators

review Full Text OpenAlex 424 FWCI51.56597719

Wnt signaling pathway: A comprehensive review

review Full Text OpenAlex 297 FWCI36.55153992

The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer

review Full Text OpenAlex 280 FWCI45.70976548

β-Catenin signaling in hepatocellular carcinoma

article Full Text OpenAlex 251 FWCI30.39808202

Apical–basal polarity and the control of epithelial form and function

review Full Text OpenAlex 249 FWCI39.34304815

Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

article Full Text OpenAlex 246 FWCI118.14081738