专题：Wnt/β-catenin signaling in development and cancer

This cluster of papers focuses on the Wnt signaling pathway and its role in development, stem cells, cancer, and disease. It covers components, mechanisms, diseases, therapeutic modalities, and the impact of Wnt signaling on osteoblast and chondrocyte differentiation.
最新文献
Identification of a novel EphB4 inhibitor, Sanguinarine, which attenuates β-catenin signaling to inhibit tumor proliferation and migration in lung cancer

article Full Text OpenAlex

Start small: A model for tissue-wide planar cell polarity without morphogens

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Spectrin coordinates cell shape and signaling essential for epidermal differentiation

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aPKC and F-actin dynamics promote Hippo pathway polarity in asymmetrically dividing neuroblasts

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Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

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Partial-EMT in oral squamous cell carcinoma: molecular circuitry and clinical translation

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Analysis of cranial tenocyte heterogeneity reveals a role for Wnt signaling in tendon attachments

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The dual role of the Notch signaling pathway in digestive system cancers

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Drosophila TRAPPC8-Rab1 module regulates retrograde trafficking of Wingless and Evi/Wntless

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The role of cohesin loading at enhancers in the flux of loop extrusion and long-range transcriptional control

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近5年高被引文献
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

review Full Text OpenAlex 2108 FWCI169.5031

Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

review Full Text OpenAlex 784 FWCI65.474

The Hippo signalling pathway and its implications in human health and diseases

review Full Text OpenAlex 629 FWCI66.8189

Ischemia-reperfusion injury: molecular mechanisms and therapeutic targets

article Full Text OpenAlex 497 FWCI120.5469

The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators

review Full Text OpenAlex 445 FWCI36.4675

Wnt signaling pathway: A comprehensive review

review Full Text OpenAlex 311 FWCI25.8748

The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer

review Full Text OpenAlex 297 FWCI32.8224

Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

article Full Text OpenAlex 292 FWCI70.8243

β-Catenin signaling in hepatocellular carcinoma

article Full Text OpenAlex 269 FWCI21.4484

Apical–basal polarity and the control of epithelial form and function

review Full Text OpenAlex 260 FWCI28.1502