专题：Complement system in diseases

This cluster of papers explores the role of the complement system in immune response, focusing on its involvement in thrombotic microangiopathies, hemolytic uremic syndrome, and inflammatory diseases. It delves into the genetics, regulation, and therapeutic interventions such as Eculizumab for managing complement-related disorders.
最新文献
Reframing SERPING1 Variants of Uncertain Significance in Hereditary Angioedema: a dynamic threshold-based conceptual framework

article Full Text OpenAlex

Probing the surrogate validity of proteinuria thresholds in C3 glomerulopathy/immune-complex membranoproliferative glomerulonephritis: unresolved biases and mechanistic gaps

article Full Text OpenAlex

Association of Serum Complement C3 with Primary Open Angle Glaucoma and its Severity

article Full Text OpenAlex

TREX1-associated thrombotic microangiopathy: a tale of 2 mechanistically distinct domains

article Full Text OpenAlex

Nanobody-based gene therapy targeting complement component C3 reduces choroidal neovascularization in mice

article Full Text OpenAlex

C1q neutralization during epileptogenesis attenuates complement‐mediated synaptic elimination and epileptiform activity

article Full Text OpenAlex

Role of a ficolin in the innate immune mechanisms of Penaeus vannamei against Vibrio parahaemolyticus

article Full Text OpenAlex

Intracellular complement Factor H promotes tumor progression through modulation of cell cycle and actin cytoskeleton

preprint Full Text OpenAlex

Plasmodium falciparum impairs Ang-1 secretion by pericytes in a 3D brain microvessel model

article Full Text OpenAlex

Thrombotic Microangiopathy (TMA) in a Heart Transplant Patient: A Complex Clinical‐Pathologic Dilemma

article Full Text OpenAlex

近5年高被引文献
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

article Full Text OpenAlex 1389 FWCI172.62569588

The roles of extracellular vesicles in the immune system

review Full Text OpenAlex 1038 FWCI127.74578598

Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Ninth Special Issue

article Full Text OpenAlex 453 FWCI87.6594643

Autoimmune Encephalitis Misdiagnosis in Adults

article Full Text OpenAlex 234 FWCI39.222784

A guide to complement biology, pathology and therapeutic opportunity

review Full Text OpenAlex 213 FWCI41.114616

Complosome — the intracellular complement system

review Full Text OpenAlex 204 FWCI40.33886853

Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection

review Full Text OpenAlex 195 FWCI24.16008652

Terminal Complement Inhibitor Ravulizumab in Generalized Myasthenia Gravis

article Full Text OpenAlex 187 FWCI31.58198192

Neutralization, effector function and immune imprinting of Omicron variants

article Full Text OpenAlex 163 FWCI46.47631861

Faricimab: First Approval

review Full Text OpenAlex 144 FWCI40.54619075