专题：Monoclonal and Polyclonal Antibodies Research

This cluster of papers focuses on the development, engineering, and applications of therapeutic antibodies, including their interaction with Fc receptors, monoclonal antibody therapy for cancer, antibody engineering techniques such as nanobodies and bispecific antibodies, the impact of glycosylation on antibody function, and antibody pharmacokinetics.
最新文献
Payload Diversification Overcomes Resistance and Guides Sequential Antibody–Drug Conjugate Therapy in Breast Cancer

article Full Text OpenAlex

BACH2 regulates T cell lineage state to enhance CAR T cell function

article Full Text OpenAlex

BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial

article Full Text OpenAlex

Protein structure-informed bacteriophage genome annotation with Phold

article Full Text OpenAlex

Engineered outer membrane vesicles enhance solid tumour CAR-T cell therapy

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AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications

article Full Text OpenAlex

Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity using CHANGE-seq-BE

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T cell engagers emerge as a compelling therapeutic modality

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Fitness Landscape for Antibodies 2: Benchmarking Reveals That Protein AI Models Cannot Yet Consistently Predict Developability Properties

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Bacterial resistance to phage therapy: Mechanisms and strategies to overcome it

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近5年高被引文献
Antibody drug conjugate: the “biological missile” for targeted cancer therapy

review Full Text OpenAlex 1387 FWCI136.6592

Teclistamab in Relapsed or Refractory Multiple Myeloma

article Full Text OpenAlex 1010 FWCI151.7188

Targeting HER2-positive breast cancer: advances and future directions

review Full Text OpenAlex 993 FWCI97.0008

Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

review Full Text OpenAlex 886 FWCI138.4287

Antibody evasion properties of SARS-CoV-2 Omicron sublineages

article Full Text OpenAlex 849 FWCI85.4788

Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5

article Full Text OpenAlex 824 FWCI81.7359

Efficacy and Safety of Trastuzumab Deruxtecan in Patients With HER2-Expressing Solid Tumors: Primary Results From the DESTINY-PanTumor02 Phase II Trial

article Full Text OpenAlex 794 FWCI184.7225

Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum

article Full Text OpenAlex 753 FWCI75.4641

Advances in covalent drug discovery

review Full Text OpenAlex 723 FWCI73.2742

Antibody–drug conjugates come of age in oncology

review Full Text OpenAlex 694 FWCI162.5897