专题：Gout, Hyperuricemia, Uric Acid

This cluster of papers explores the role of uric acid in cardiovascular and renal health, focusing on its association with hyperuricemia, gout, hypertension, endothelial dysfunction, and metabolic syndrome. The papers also discuss the impact of xanthine oxidase inhibitors and the inflammatory pathways related to uric acid.
最新文献
Multicomponent reaction synthesis and evaluation of novel 3,4-dihydropyrazine[1,2-b]Indazole-1(2H)-one derivatives as inhibitors of pyroptosis and inflammation

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Sinomenine hydrochloride alleviates autoimmune myocarditis via suppressing Th1 cell induced-M1 macrophage pyroptosis

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Associations of genetic proxies for non-steroidal anti-inflammatory drugs with increased kidney stone risk: a Mendelian randomization study

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Novel GSDMD inhibitor GI-Y1 attenuates sepsis-induced myocardial dysfunction by targeting Gasdermin D and inhibiting Gasdermin D-mediated pyroptosis

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Distinct right ventricular performance in response to acute colchicine treatment in healthy and diseased states.

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Medication adherence and health empowerment in gout: a cross-sectional survey of patients

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2024 Update of Chinese Guidelines for Diagnosis and Treatment of Hyperuricemia and Gout Part I: Recommendations for General Patients

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Elevated uric acid and impaired triglyceride metabolism predict mortality in women after ischemic stroke

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Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases

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Prognostic impact of uric acid levels in heart failure with mildly reduced ejection fraction: Insights from a large retrospective registry

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近5年高被引文献
Pyroptosis: mechanisms and diseases

review Full Text OpenAlex 1745 FWCI40.198

NLRP3 inflammasome activation and cell death

review Full Text OpenAlex 1054 FWCI23.627

Gout

review Full Text OpenAlex 931 FWCI30.575

NLRP3 inflammasome in cancer and metabolic diseases

review Full Text OpenAlex 846 FWCI19.645

An update on the regulatory mechanisms of NLRP3 inflammasome activation

review Full Text OpenAlex 606 FWCI13.175

NLRP3 and pyroptosis blockers for treating inflammatory diseases

review Full Text OpenAlex 506 FWCI17.616

Role of pyroptosis in inflammation and cancer

review Full Text OpenAlex 490 FWCI16.742

Pyroptosis in inflammatory diseases and cancer

review Full Text OpenAlex 459 FWCI15.659

Molecular Biological and Clinical Understanding of the Pathophysiology and Treatments of Hyperuricemia and Its Association with Metabolic Syndrome, Cardiovascular Diseases and Chronic Kidney Disease

review Full Text OpenAlex 399 FWCI12.45

From purines to purinergic signalling: molecular functions and human diseases

review Full Text OpenAlex 338 FWCI11.619