专题：Advanced Glycation End Products research

This cluster of papers focuses on the biochemistry and molecular cell biology of diabetic complications, particularly exploring the role of Advanced Glycation End Products (AGEs), HMGB1, oxidative stress, inflammation, and the receptor for AGEs (RAGE) in the pathobiology of diabetes. The papers also delve into the involvement of mitochondrial superoxide, toll-like receptors, necrotic cells, and cellular signaling pathways in diabetic complications.
最新文献
Revisiting metformin as a geroprotector

article Full Text OpenAlex

A metabolic alarmin from keratinocytes potentiates systemic humoral immunity

article Full Text OpenAlex

Repurposing a detrimental antibody epitope as targeted therapeutics for sepsis and rheumatoid arthritis

article Full Text OpenAlex

Impact of Impaired Fasting or Diabetes Compared with That of Smoking Habit on Tooth Loss

article Full Text OpenAlex

The redox-sensitive protein HMGB1: intracellular and extracellular roles

article Full Text OpenAlex

Cross-talk between lipopolysaccharide tolerance and AGEs in the regulation of macrophage inflammation and cholesterol efflux

article Full Text OpenAlex

Glycosylation engineering in protein modification: Mechanistic insights, food applications, and potential health risks

article Full Text OpenAlex

Mammals that can develop type 2 diabetes have a similarly structured β-sheet amyloid oligomer

article Full Text OpenAlex

Unraveling the connection: Inflammatory markers and diabetes mellitus pathogenesis

article Full Text OpenAlex

A Computational Strategy for Validation of Piperidine as Lead from Phytochemical evaluation for Antiglycation activity via AGEs-RAGE Pathway Modulation

article Full Text OpenAlex

近5年高被引文献
The mechanism of HMGB1 secretion and release

review Full Text OpenAlex 786 FWCI95.842

Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives

review Full Text OpenAlex 784 FWCI92.7329

Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs

review Full Text OpenAlex 676 FWCI81.6482

Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives

review Full Text OpenAlex 615 FWCI72.7643

Hyperglycemia and Oxidative Stress: An Integral, Updated and Critical Overview of Their Metabolic Interconnections

review Full Text OpenAlex 593 FWCI108.4874

Oxidative Stress in Type 2 Diabetes: Impacts from Pathogenesis to Lifestyle Modifications

review Full Text OpenAlex 467 FWCI85.4361

Oxidative Stress in Ageing and Chronic Degenerative Pathologies: Molecular Mechanisms Involved in Counteracting Oxidative Stress and Chronic Inflammation

review Full Text OpenAlex 404 FWCI29.7377

ROS: Basic Concepts, Sources, Cellular Signaling, and its Implications in Aging Pathways

review Full Text OpenAlex 392 FWCI42.3111

Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation

review Full Text OpenAlex 387 FWCI103.8533

Maillard reaction chemistry in formation of critical intermediates and flavour compounds and their antioxidant properties

review Full Text OpenAlex 369 FWCI41.9055