专题:Enzyme Structure and Function

This cluster of papers encompasses advancements in macromolecular crystallography techniques, including automated model building, small-angle scattering for structural analysis, protein stability assessment, and high-throughput crystallization methods. It also covers topics such as enzyme structure determination, X-ray solution scattering, and data processing for structure solution.
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Updates to the CASP Infrastructure in 2024

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Crystal structure of a seven-substitution mutant of hydroxynitrile lyase from rubber tree

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Residual flexibility in the topologically constrained multivalent complex between the GKAP scaffold and LC8 hub proteins

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Synthesis and application of nanoscale ZIF-67 for enhanced phospholipase A1 immobilization and high phospholipid-DHA conversion

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DR and SPIT: Statistical approaches for identifying transient structure in intrinsically disordered proteins via NMR chemical shifts

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Thermotolerant class A acid phosphatase active across broad pH range and diverse substrates

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Cold stress enhances cryotolerance in Lacticaseibacillus rhamnosus B6 via membrane lipid remodeling and differential protein expression

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Are high Z' polymorphs metastable? Insight from pharmaceutical polymorphs

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Pathway regulation mechanism by cotranslational protein folding

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Enzymatic P–O Bond Cleavage: Criteria of Dissociative and Associative Mechanisms

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近5年高被引文献
Highly accurate protein structure prediction with AlphaFold

article Full Text OpenAlex 34250 FWCI2186.374

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

article Full Text OpenAlex 6650 FWCI442.52

Accurate prediction of protein structures and interactions using a three-track neural network

article Full Text OpenAlex 4513 FWCI302.744

Protein complex prediction with AlphaFold-Multimer

preprint Full Text OpenAlex 3271 FWCI0

InterPro in 2022

article Full Text OpenAlex 2006 FWCI188.474

The carbohydrate-active enzyme database: functions and literature

article Full Text OpenAlex 1728 FWCI105.221

Sotorasib for Lung Cancers with KRAS p.G12C Mutation

article Full Text OpenAlex 1377 FWCI90.745

AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

article Full Text OpenAlex 949 FWCI108.447

Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures

article Full Text OpenAlex 897 FWCI57.981

Improved prediction of protein-protein interactions using AlphaFold2

article Full Text OpenAlex 794 FWCI74.225