专题:Enzyme Structure and Function

This cluster of papers encompasses advancements in macromolecular crystallography techniques, including automated model building, small-angle scattering for structural analysis, protein stability assessment, and high-throughput crystallization methods. It also covers topics such as enzyme structure determination, X-ray solution scattering, and data processing for structure solution.
最新文献
PDXK Mutation Causes a Late-Onset Pyridoxal 5’-Phosphate-Responsive Peripheral Neuropathy Preceded by Neonatal Seizures: Correspondence

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Pseudomonas aeruginosa Relies on a Phosphoketolase to Support Anaerobic Survival Under Reductive Stress

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Deep models of protein evolution in time generate realistic evolutionary trajectories and functional proteins

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Ectopic expression of cytosolic DHODH uncouples de novo pyrimidine biosynthesis from mitochondrial electron transport

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Round robin on structure analysis from 3D electron diffraction data

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A geometric foundation model for enzyme retrieval with evolutionary insights

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PRIZM: Combining Low-N Data and Zero-shot Models to Design Enhanced Protein Variants

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Atomic resolution ensembles of intrinsically disordered proteins with Alphafold

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Hierarchical friction memory leads to subdiffusive configurational dynamics of fast-folding proteins

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Integrated structural dynamics uncover a new B12 photoreceptor activation mode

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近5年高被引文献
InterPro in 2022

article Full Text OpenAlex 2475 FWCI218.2479

AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

article Full Text OpenAlex 1684 FWCI162.9804

Improved prediction of protein-protein interactions using AlphaFold2

article Full Text OpenAlex 964 FWCI81.1924

Dali server: structural unification of protein families

article Full Text OpenAlex 946 FWCI78.0931

RCSB Protein Data Bank (RCSB.org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning

article Full Text OpenAlex 813 FWCI57.2446

The CCP4 suite: integrative software for macromolecular crystallography

article Full Text OpenAlex 768 FWCI74.082

Generalized biomolecular modeling and design with RoseTTAFold All-Atom

article Full Text OpenAlex 745 FWCI178.872

A structural biology community assessment of AlphaFold2 applications

article Full Text OpenAlex 665 FWCI56.2968

DALI shines a light on remote homologs: One hundred discoveries

article Full Text OpenAlex 657 FWCI53.1741

An atlas of substrate specificities for the human serine/threonine kinome

article Full Text OpenAlex 646 FWCI96.9212