专题：Adenosine and Purinergic Signaling

This cluster of papers focuses on the molecular physiology and pharmacology of purinergic signalling, including the role of adenosine receptors, P2X receptors, and nucleotide signalling in immune suppression, inflammation, neuroprotection, and the tumor microenvironment. It explores the potential therapeutic targets related to purinergic signalling.
最新文献
Extracellular GPX4 impairs antitumor immunity via dendritic ZP3 receptors

article Full Text OpenAlex

Investigating the Association Between P2Y12 Receptor, SV2A, and Tau Expression in Postmortem AD and Control Brains Using In Vitro Autoradiography

article Full Text OpenAlex

Nicardipine protects against gentamicin-induced nephrotoxicity: Potential involvement of IL-23R, NRF2, and Beclin-1 perturbation

article Full Text OpenAlex

Genetic Variations in the P2X7 Receptor: Opportunities and Challenges for Drug Development

review Full Text OpenAlex

Isoquinoline-Derived Half-Sandwich Ru(II) Arene Complex Potentiates Antitumor Chemoimmunotherapeutic Response

article Full Text OpenAlex

Transcriptional and epigenetic targets of MEF2C in human microglia contribute to cellular functions related to autism risk and age-related disease

article Full Text OpenAlex

Lysine acetyltransferase 2A-mediated succinylation of adenosine monophosphate-activated protein kinase suppresses gallstone formation by inhibiting inflammation and pyroptosis

article Full Text OpenAlex

Paradoxical role and therapeutic potential of autophagy in lymphomas

review Full Text OpenAlex

Gut microbiota butyrate mediated RUNX3 promotes Nr4a1 high ZFP36 high resident macrophages via NR4A1/ERK1/2 MAPK to maintain gut homeostasis

article Full Text OpenAlex

Targeting the NLRP3 inflammasome with natural products for ischemia–reperfusion injury across organs: mechanisms, structure–activity relationships, and delivery innovations

review Full Text OpenAlex

近5年高被引文献
Nucleotide metabolism: a pan-cancer metabolic dependency

review Full Text OpenAlex 375 FWCI72.78279979

Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials

review Full Text OpenAlex 303 FWCI38.52064645

Targeting inflammation to treat diabetic kidney disease: the road to 2030

review Full Text OpenAlex 296 FWCI57.73938947

CD39/CD73/A2AR pathway and cancer immunotherapy

review Full Text OpenAlex 271 FWCI86.00358955

Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes

article Full Text OpenAlex 212 FWCI41.90115416

Biomarker of Neuroinflammation in Parkinson’s Disease

review Full Text OpenAlex 206 FWCI34.63830275

Adenosine and Adenine Nucleotides As Regulators of Cellular Function

book Full Text OpenAlex 199 FWCI2.11111111

Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation

article Full Text OpenAlex 195 FWCI41.01473077

ER-Targeting Cyanine Dye as an NIR Photoinducer to Efficiently Trigger Photoimmunogenic Cancer Cell Death

article Full Text OpenAlex 183 FWCI20.09052395

Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease

article Full Text OpenAlex 177 FWCI23.01053238