专题：Ion Channels and Receptors

This cluster of papers focuses on the role of calcium signaling and ion channels, particularly TRP channels, in sensory neurons and their involvement in thermosensation, nociception, and the pain pathway. It also explores the function of store-operated channels, Orai1, and STIM1 in calcium homeostasis and signaling. The papers cover a wide range of topics related to calcium signaling in sensory perception and disease.
最新文献
Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity

article Full Text OpenAlex

Code for "N-palmitoyl glycine differentially modulates TRPM4 and TRPC5 and is causally linked to Brugada syndrome"

article Full Text OpenAlex

Structural mechanism of the agonist binding on human TRPC3 channel

article Full Text OpenAlex

TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms

article Full Text OpenAlex

DHHC21 is a STIM1 protein S-acyltransferase that modulates immune function in vivo

preprint Full Text OpenAlex

Structural basis for agonist and heat activation of nociceptor TRPM3

article Full Text OpenAlex

Molecular characterization of TRPA1 and its function in thermotaxis and molting in Portunus trituberculatus

article Full Text OpenAlex

Platelet Signal Transduction: Calcium

book-chapter Full Text OpenAlex

Lysosomal Ca 2+ Release Through TRPML1 Governs Ventricular Arrhythmia After Myocardial Infarction

article Full Text OpenAlex

Store-operated calcium entry as an important mechanism of tumor adaptation to an aggressive microenvironment

article Full Text OpenAlex

近5年高被引文献
TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases

review Full Text OpenAlex 380 FWCI106.06810389

Cough hypersensitivity and chronic cough

review Full Text OpenAlex 260 FWCI52.24911553

Advances and challenges in therapeutic targeting of NRF2

review Full Text OpenAlex 203 FWCI37.69109275

Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection

article Full Text OpenAlex 177 FWCI40.15880304

TRP channels in thermosensation

review Full Text OpenAlex 149 FWCI22.79135967

Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha‐Synuclein and Enhance Therapy of Parkinson's Disease

article Full Text OpenAlex 135 FWCI20.78941592

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

article Full Text OpenAlex 134 FWCI28.61277949

PIEZO1 transduces mechanical itch in mice

article Full Text OpenAlex 134 FWCI23.87301706

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

review Full Text OpenAlex 133 FWCI29.10144359

The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors

review Full Text OpenAlex 131 FWCI24.3228234