专题：Ion Channels and Receptors

This cluster of papers focuses on the role of calcium signaling and ion channels, particularly TRP channels, in sensory neurons and their involvement in thermosensation, nociception, and the pain pathway. It also explores the function of store-operated channels, Orai1, and STIM1 in calcium homeostasis and signaling. The papers cover a wide range of topics related to calcium signaling in sensory perception and disease.
最新文献
TRPM7 kinase inhibitor TG100-115 provides neuroprotection against neonatal hypoxic-ischemic brain injury

article Full Text OpenAlex

Rescuing the heart from the tornadoes of sudden cardiac death

article Full Text OpenAlex

Piezo2 inhibition enhances the survival and axonal regeneration of spinal motoneurons after brachial plexus avulsion

article Full Text OpenAlex

Matching sodium channel availability to resting membrane potential: Biophysical logic across excitable cell types

article Full Text OpenAlex

The pharmacological rationale for amiloride nasal spray: potentially a portable and rapid-acting treatment for panic disorder

article Full Text OpenAlex

The nonexcitable smooth muscle: remodeling the smooth muscle ion transport toolkit in disease

article Full Text OpenAlex

Temperature-dependent gating pathways in TRPV3

article Full Text OpenAlex

Structural energetics of cold sensitivity

article Full Text OpenAlex

Oxidative Stress and the KEAP1/NRF2 Axis in Saphenous Vein: Implications for Graft Patency

article Full Text OpenAlex

TRPV4 acetylation in prenatal liver prevents low glucose-induced inhibition of mTORC1 and safeguards fetal development

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近5年高被引文献
TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases

review Full Text OpenAlex 449 FWCI87.5813

Cough hypersensitivity and chronic cough

review Full Text OpenAlex 281 FWCI39.0006

Advances and challenges in therapeutic targeting of NRF2

review Full Text OpenAlex 234 FWCI34.7617

Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection

article Full Text OpenAlex 200 FWCI28.5916

TRP channels in thermosensation

review Full Text OpenAlex 163 FWCI18.8264

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

article Full Text OpenAlex 151 FWCI19.0992

PIEZO1 transduces mechanical itch in mice

article Full Text OpenAlex 150 FWCI15.9808

The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors

review Full Text OpenAlex 145 FWCI21.4969

Gut enterochromaffin cells drive visceral pain and anxiety

article Full Text OpenAlex 142 FWCI38.1257

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

review Full Text OpenAlex 141 FWCI22.3613