专题：Ion Channels and Receptors

This cluster of papers focuses on the role of calcium signaling and ion channels, particularly TRP channels, in sensory neurons and their involvement in thermosensation, nociception, and the pain pathway. It also explores the function of store-operated channels, Orai1, and STIM1 in calcium homeostasis and signaling. The papers cover a wide range of topics related to calcium signaling in sensory perception and disease.
最新文献
Role of TRPV4 Channels in the Development and Stabilization of Atherosclerotic Plaques

grant Full Text OpenAlex

Transient receptor potential channels TRPA1 and TRPV1 are involved in chronic pain relief via Pulsed Radiofrequency in Rheumatoid Arthritis rat

article Full Text OpenAlex

Lysosomal TMEM165 controls cellular ion homeostasis and survival by mediating lysosomal Ca2+ import and H+ efflux

article Full Text OpenAlex

Identifying substances suspected of facilitating inhalation or increasing nicotine uptake as part of the enforcement of the Tobacco Products Directive

editorial Full Text OpenAlex

Development and in vitro characterization of humanized antibodies for blocking human TRPM4 channel

article Full Text OpenAlex

Capsaicin from <i>Capsicum annuum</i> var. Cayenne: Isolation, GC-MS Analysis, Anticancer Activity on MG63 Osteosarcoma Cells, and <i>In Silico</i> Interaction with 6T2W

article Full Text OpenAlex

Soluble β-Amyloid Oligomers Selectively Upregulate TRPC3 in Excitatory Neurons via Calcineurin-Coupled NFAT

article Full Text OpenAlex

CRAC channels and patho-physiology of peripheral organ systems

article Full Text OpenAlex

Nociceptor-specific signaling of the receptor guanylyl cyclase Npr2 contributes to acute and persistent pain

article Full Text OpenAlex

Transient receptor potential vanilloid 2 (TRPV2) channels modulate the nigrostriatal dopaminergic activity in rats

article Full Text OpenAlex

近5年高被引文献
Advances in TRP channel drug discovery: from target validation to clinical studies

review Full Text OpenAlex 398 FWCI18.438

TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases

review Full Text OpenAlex 214 FWCI23.268

Cough hypersensitivity and chronic cough

review Full Text OpenAlex 199 FWCI13.294

NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation

article Full Text OpenAlex 195 FWCI13.535

Structural snapshots of TRPV1 reveal mechanism of polymodal functionality

article Full Text OpenAlex 179 FWCI18.838

Heat-dependent opening of TRPV1 in the presence of capsaicin

article Full Text OpenAlex 167 FWCI16.837

TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway

article Full Text OpenAlex 166 FWCI17.322

Advances and challenges in therapeutic targeting of NRF2

review Full Text OpenAlex 146 FWCI9.435

Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection

article Full Text OpenAlex 135 FWCI32.533

Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel

article Full Text OpenAlex 134 FWCI13.54