专题:Bone Metabolism and Diseases

This cluster of papers explores the molecular mechanisms underlying osteoclast differentiation, bone resorption, and the regulation of bone homeostasis. It delves into the signaling pathways, transcription factors, and cytokines involved in osteoclast and osteoblast differentiation, as well as the interplay between the immune system and bone metabolism. Additionally, it investigates the impact of oxidative stress and inflammatory cytokines on bone remodeling.
最新文献
Gut Microbiota Regulates Brain–Bone Axis to Influence Osteoporosis Pathogenesis and Treatment

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Cell signaling and transcriptional regulation of osteoclast lineage commitment, differentiation, bone resorption and diseases

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TGF-β/BMP signaling in skeletal biology: molecular mechanisms, regulatory networks, and therapeutic implications in development, regeneration, and disease

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Mechanical rejuvenation of senescent stem cells and aged bone via chromatin remodeling

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Biologics for bone regeneration: advances in cell, protein, gene, and mRNA therapies

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Mapping somatosensory afferent circuitry to bone identifies neurotrophic signals required for fracture healing

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Osteoporosis After Menopause and After Drug Therapy: The Molecular Mechanism of Bone Loss and Its Treatment

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Inflammatory bone loss and signaling pathways in periodontitis: mechanistic insights and emerging therapeutic strategies

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Piezo1-driven mechanotransduction regulates mitochondrial biogenesis by AMPK/SIRT1-mediated PGC-1α deacetylation to ameliorate bone loss in disuse osteoporosis

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Gut microbiota preserves bone mass through modulating the hyodeoxycholic acid–TGR5 axis

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