专题:Neuroinflammation and Neurodegeneration Mechanisms

This cluster of papers focuses on the role of microglia, neuroinflammation, and neurodegeneration in various neurological disorders such as Alzheimer's disease, ischemic stroke, and traumatic brain injury. It also explores the involvement of astrocytes, synaptic pruning, TREM2, cytokines, and innate immunity in the pathophysiology of these disorders.
最新文献
Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons

article Full Text OpenAlex

SIK2 mediated mitochondrial homeostasis in spinal cord injury: modulating oxidative stress and the AIM2 inflammasome via CRTC1/CREB signaling

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The effect of shingles vaccination at different stages of the dementia disease course

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“Rewiring brain immunity: targeting microglial metabolism for neuroprotection in neurodegenerative disorders”

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IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness

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A transcriptomic atlas of astrocyte heterogeneity across space and time in mouse and marmoset

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Valeric Acid: A Gut-Derived Metabolite as a Potential Epigenetic Modulator of Neuroinflammation in the Gut–Brain Axis

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Dietary choline-derived Trimethylamine N-oxide impairs hippocampal neuronal function via PANoptosis activation

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Pediococcus acidilactici attenuates chronic stress-induced depression via generating metabolite indole-3-lactic acid and downregulating neuroinflammation

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Tanshinone IIA attenuates cerebral-ischemia-reperfusion-induced neuroinflammation by inhibiting the TLR4/NF-κB signaling cascade: A study integrating network pharmacology, bioinformatics, and experimental validation

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近5年高被引文献
Lecanemab in Early Alzheimer’s Disease

article Full Text OpenAlex 4751 FWCI530.2083

Microglia states and nomenclature: A field at its crossroads

review Full Text OpenAlex 1724 FWCI135.6962

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

article Full Text OpenAlex 1492 FWCI182.6911

Role of neuroinflammation in neurodegeneration development

review Full Text OpenAlex 1261 FWCI226.2331

Inflammation and immune dysfunction in Parkinson disease

review Full Text OpenAlex 1230 FWCI144.1516

Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets

review Full Text OpenAlex 1161 FWCI145.1055

Inflammation and aging: signaling pathways and intervention therapies

review Full Text OpenAlex 1118 FWCI199.4944

A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

article Full Text OpenAlex 911 FWCI142.2658

An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases

review Full Text OpenAlex 885 FWCI96.3145

Mitochondrial dysfunction in cell senescence and aging

review Full Text OpenAlex 878 FWCI93.58