专题：Cancer Genomics and Diagnostics

This cluster of papers focuses on the genomic landscape of cancer, mutational signatures, intratumor heterogeneity, liquid biopsies, somatic mutations, tumor evolution, cell-free DNA, genomic instability, targeted therapy, and clonal evolution in various cancer types.
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Large-scale, spatially resolved panoramic CRISPR screening in native tissue environments using Perturb-DBiT

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AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology

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Non-invasive profiling of the tumour microenvironment with spatial ecotypes

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Advancing AI for multi-omics and clinical data integration in basic and translational cancer research

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Risk-adaptive therapy guided by dynamic ctDNA in nasopharyngeal carcinoma

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The Pathologic Response Evaluation and Detection in Circulating Tumor-DNA Study: Ultrasensitive Circulating Tumor-DNA Assessment of Breast Cancer Minimal Residual Disease

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Monitoring of plasma and urine tumor-derived DNA to inform bladder-sparing approaches for patients with muscle-invasive bladder cancer

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Omics medicine: what the clinicians should know

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The Transformative Potential of Liquid Biopsies and Circulating Tumor DNA (ctDNA) in Modern Oncology

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Advances and challenges in single-cell RNA sequencing data analysis: a comprehensive review

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