专题:Single-cell and spatial transcriptomics

This cluster of papers focuses on the comprehensive integration and analysis of single-cell transcriptomic data, covering topics such as cell types, spatial profiling, lineage tracking, data integration, gene expression, and cell heterogeneity. The research explores various technologies and computational methods to study the transcriptomic landscape at the single-cell level.
最新文献
TRIDENT Case Card: Spatial Transcriptomics of the Gut Host–Microbiome Interface (Ntekas et al., 2026)

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Spatial transcriptomics maps host–gut microbiome biogeography at high resolution

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Single-cell spatial proteomics maps human liver zonation patterns and their vulnerability to disruption in tissue architecture

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Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis

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Advances and challenges in single-cell RNA sequencing data analysis: a comprehensive review

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Single-cell proteomic landscape of the developing human brain

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Critical role for a high-plasticity cell state in lung cancer

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Impact and correction of segmentation errors in spatial transcriptomics

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Cellular neighborhoods in cancer

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Robust and interpretable prediction of gene markers and cell types from spatial transcriptomics data

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近5年高被引文献
Dictionary learning for integrative, multimodal and scalable single-cell analysis

article Full Text OpenAlex 4417 FWCI662.4022

Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

article Full Text OpenAlex 1607 FWCI127.14

Human organs-on-chips for disease modelling, drug development and personalized medicine

review Full Text OpenAlex 1332 FWCI95.7158

Single‐cell RNA sequencing technologies and applications: A brief overview

review Full Text OpenAlex 1220 FWCI97.5032

CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data

article Full Text OpenAlex 1190 FWCI94.3831

Cell2location maps fine-grained cell types in spatial transcriptomics

article Full Text OpenAlex 1166 FWCI94.9031

Museum of spatial transcriptomics

review Full Text OpenAlex 1152 FWCI90.8237

Cross-tissue immune cell analysis reveals tissue-specific features in humans

article Full Text OpenAlex 1094 FWCI86.4961

Methods and applications for single-cell and spatial multi-omics

review Full Text OpenAlex 1065 FWCI157.15

GSEApy: a comprehensive package for performing gene set enrichment analysis in Python

article Full Text OpenAlex 1039 FWCI79.8226