专题：Sphingolipid Metabolism and Signaling

This cluster of papers explores the role of sphingolipids, including sphingosine-1-phosphate and ceramide, in signaling and metabolism, with implications for health and disease such as lymphocyte egress, insulin resistance, cancer, and apoptosis.
最新文献
Neuroprotective effects of Platycladus orientalis ethyl acetate fraction on retinal Müller cells: modulation of AKT1/mTOR and Raf-1/MEK1/2 pathways via AMPK activation

article Full Text OpenAlex

DKC1 promotes colorectal cancer progression and therapy resistance by dysregulating sphingolipid biosynthesis

article Full Text OpenAlex

Inhibition of ceramide synthesis ameliorates body wasting in a cancer cachexia model

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Resolution of Skeletal Muscle Inflammation: Role of Specialized Pro-resolving Lipid Mediators in the Recovery from Exercise, Injury, and Disease

book-chapter Full Text OpenAlex

Flavonoids from Elsholtzia ciliata restore redox electron flow and metabolic signaling via PTP1B inhibition in muscle and liver cells

article Full Text OpenAlex

Olipudase alfa IgE‐mediated anaphylaxis prevented by omalizumab and tailored desensitization in a child with acid sphingomyelinase deficiency

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The S1PR modulator Ozanimod reverses spine deficits, Amyloid-β plaques deposition and neuroinflammation in aged APP/PS1 mice

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Phosphatidylinositol-3-kinase/Protein Kinase B (PI3K/AKT) and Nucleotide-Binding Oligomerization Domain-like Receptor Family Pyrin Domain Containing 3 (NLRP3) Inflammasome Modulation Underlies the Neuroprotective Effects of Vildagliptin in a Rotenone-Induced Mouse Model of Parkinson’s Disease

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Relapse-associated worsening in apolipoprotein E ε4 carriers with relapsing multiple sclerosis

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Caveolin-1 deficiency improved glucose metabolism via modulation of β-cell autophagy in high-fat diet-fed mice

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近5年高被引文献
Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets

review Full Text OpenAlex 431 FWCI103.4119

Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

article Full Text OpenAlex 376 FWCI101.1381

Comprehensive metabolomics expands precision medicine for triple-negative breast cancer

article Full Text OpenAlex 322 FWCI24.2782

Atropisomerism in the Pharmaceutically Relevant Realm

article Full Text OpenAlex 300 FWCI28.1963

Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice

article Full Text OpenAlex 267 FWCI54.1047

Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides

article Full Text OpenAlex 260 FWCI47.1654

Dynamic lipidome alterations associated with human health, disease and ageing

article Full Text OpenAlex 236 FWCI33.3466

IL-10 constrains sphingolipid metabolism to limit inflammation

article Full Text OpenAlex 218 FWCI43.7484

Organocatalytic Atroposelective Synthesis of N−N Axially Chiral Indoles and Pyrroles by De Novo Ring Formation

article Full Text OpenAlex 174 FWCI18.2011

Extraction, structure, and activity of polysaccharide from Radix astragali

review Full Text OpenAlex 171 FWCI32.5446