专题：Sphingolipid Metabolism and Signaling

This cluster of papers explores the role of sphingolipids, including sphingosine-1-phosphate and ceramide, in signaling and metabolism, with implications for health and disease such as lymphocyte egress, insulin resistance, cancer, and apoptosis.
最新文献
Tissue-specific fibroblast lipid cues impose the rate of epithelial cancer invasion

article Full Text OpenAlex

Unveiling the impact of colonic pH and pH-sensing receptors in blood pressure regulation

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

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Bioprospecting c-di-GMP-activated exopolysaccharides in bacteria: isolation of a novel atypical sphingan

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Sphingosine-1-phosphate induces pulmonary artery smooth muscle cell proliferation, migration and pulmonary arterial remodeling by modulating sonic hedgehog signaling effector FoxM1

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Pan-tumor activity of olomorasib, a next-generation KRAS G12C inhibitor in KRAS G12C-mutant advanced solid tumors: a first-in-human study

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Lipidomic profiling in metastatic prostate cancer captures tumor metabolic rewiring and its modulation by androgen receptor–targeting therapy

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Fingolimod normalizes metabolic signatures associated with synaptic plasticity and memory in APP/PS1 model: Sphingosine-1-phosphate receptor a therapeutic target for Alzheimer’s

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Noncanonical function of sphingosine kinase 2 (SPHK2) sustains hepatic triglyceride homeostasis

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Discriminative Plasma Lipidomic Signatures of Dementia with Lewy Bodies and Alzheimer’s Disease: A Targeted Mass Spectrometry and Machine Learning Approach

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近5年高被引文献
Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets

review Full Text OpenAlex 387 FWCI99.9722

Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

article Full Text OpenAlex 359 FWCI101.2004

Comprehensive metabolomics expands precision medicine for triple-negative breast cancer

article Full Text OpenAlex 310 FWCI24.2901

Atropisomerism in the Pharmaceutically Relevant Realm

article Full Text OpenAlex 294 FWCI28.1943

Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice

article Full Text OpenAlex 262 FWCI57.5436

Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides

article Full Text OpenAlex 250 FWCI47.1566

Dynamic lipidome alterations associated with human health, disease and ageing

article Full Text OpenAlex 220 FWCI32.5663

IL-10 constrains sphingolipid metabolism to limit inflammation

article Full Text OpenAlex 208 FWCI45.0292

Organocatalytic Atroposelective Synthesis of N−N Axially Chiral Indoles and Pyrroles by De Novo Ring Formation

article Full Text OpenAlex 174 FWCI18.2105

Extraction, structure, and activity of polysaccharide from Radix astragali

review Full Text OpenAlex 164 FWCI32.5576