专题：Genomics, phytochemicals, and oxidative stress

This cluster of papers focuses on the role of Nrf2 signaling in oxidative stress response, including its activation by oxidative stress, regulation of antioxidant gene expression, and its impact on cancer, inflammation, and chemoprevention. The Keap1-Nrf2-ARE pathway and the chemical diversity of glucosinolates are also central to this topic.
最新文献
Interplay of oxidative stress, cellular communication and signaling pathways in cancer

article Full Text OpenAlex

Morin Reactivates Nrf2 by Targeting Inhibition of Keap1 to Alleviate Deoxynivalenol-Induced Intestinal Oxidative Damage

article Full Text OpenAlex

Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors

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Moderate Hypothermia Alleviates Sepsis-Associated Acute Lung Injury by Suppressing Ferroptosis Induced by Excessive Inflammation and Oxidative Stress via the Keap1/GSK3β/Nrf2/GPX4 Signaling Pathway

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Epigenetic remodeling under oxidative stress: Mechanisms driving tumor metastasis

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Hyperoside induces ferroptosis in chronic myeloid leukemia cells by targeting NRF2

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Multi-omics analysis combined with network pharmacology revealed the mechanisms of rutaecarpine in chronic atrophic gastritis

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Quercetin Regulates the Polarization of Microglia through the NRF2/HO1 Pathway and Mitigates Alzheimer's Disease

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Multitarget Effects of Nrf2 Signalling in the Brain: Common and Specific Functions in Different Cell Types

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Oxidative stress and NRF2 signaling in kidney injury

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近5年高被引文献
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

review Full Text OpenAlex 2407 FWCI172.43733138

Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging

review Full Text OpenAlex 1702 FWCI443.22686858

Reactive oxygen species in cancer: Current findings and future directions

review Full Text OpenAlex 787 FWCI47.40075964

Nrf2 and Oxidative Stress: A General Overview of Mechanisms and Implications in Human Disease

review Full Text OpenAlex 671 FWCI82.57940501

Oxidative Stress in Cancer Cell Metabolism

review Full Text OpenAlex 585 FWCI45.80329728

Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer

review Full Text OpenAlex 566 FWCI37.64751692

Role of Oxidative Stress in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Implications for Prevention and Therapy

review Full Text OpenAlex 456 FWCI66.83099986

Selenium Compounds as Novel Potential Anticancer Agents

review Full Text OpenAlex 435 FWCI58.0521854

Beneficial and Detrimental Effects of Reactive Oxygen Species on Lifespan: A Comprehensive Review of Comparative and Experimental Studies

review Full Text OpenAlex 432 FWCI37.58628067

Nrf2/Keap1/ARE signaling: Towards specific regulation

review Full Text OpenAlex 427 FWCI27.69920934