专题：Tryptophan and brain disorders

This cluster of papers explores the intricate relationship between the immune system and the brain, focusing on neuroinflammation, cytokine signaling, and the impact of immune activation on psychiatric disorders such as depression and schizophrenia. The role of tryptophan metabolism, oxidative stress, and maternal immune activation in influencing brain function and behavior is also a key area of investigation.
最新文献
Metabolic adaptations rewire CD4+ T cells in a subset-specific manner in human critical illness with and without sepsis.

article Full Text OpenAlex

Aging Converts Microglial Repopulation into Maladaptive Reprogramming that Exacerbates Cognitive Deficits

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Targeting Inflammation: How Meta-Analysis Can Advance Precision Psychiatry

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Elevated sCD14 in cerebrospinal fluid: a surrogate marker for HIV-associated neurocognitive disorders in Brazil

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Zinc Ameliorates LPS-Induced Depressive-Like Behaviors Via Modulating Microglial Polarization

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Metabolic regulation of immunity in the tumor microenvironment

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N-acetylcysteine (NAC) ameliorates ethanol-induced oxidative stress, neuroinflammation, and cognitive dysfunction in APP/PS1 mouse model

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Gut Microbiota Dysbiosis and Neuroimmune Alterations in a Postmenopausal-Stress Rat Model

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Polygenic liability to C-reactive protein defines immunometabolic depression phenotypes and influences antidepressant therapeutic outcomes

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From cognition in the body to the body in cognition

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近5年高被引文献
Microbiota in health and diseases

review Full Text OpenAlex 2531 FWCI308.90358653

Multiple early factors anticipate post-acute COVID-19 sequelae

article Full Text OpenAlex 1120 FWCI191.18984754

An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases

review Full Text OpenAlex 831 FWCI145.57155516

The serotonin theory of depression: a systematic umbrella review of the evidence

review Full Text OpenAlex 802 FWCI84.79067655

A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Nanotherapeutics

review Full Text OpenAlex 723 FWCI128.16040738

Tryptophan metabolism in health and disease

review Full Text OpenAlex 676 FWCI108.59824954

Major depressive disorder: hypothesis, mechanism, prevention and treatment

article Full Text OpenAlex 650 FWCI225.25930448

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

review Full Text OpenAlex 646 FWCI309.75946021

Oxidative stress: The core pathogenesis and mechanism of Alzheimer’s disease

review Full Text OpenAlex 625 FWCI110.39026686

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

article Full Text OpenAlex 592 FWCI68.84844394