专题：RNA modifications and cancer

This cluster of papers explores the diverse landscape of RNA methylation, with a focus on m6A modification, its impact on gene expression, ribosome biogenesis, and its role in cancer progression. The research covers various aspects such as m6A-seq, tRNA fragments, YTHDF proteins, and the involvement of methyltransferases in mRNA modification.
最新文献
RiNALMo: general-purpose RNA language models can generalize well on structure prediction tasks

article Full Text OpenAlex

Intra-amniotic antisense oligonucleotide treatment improves phenotypes in preclinical models of spinal muscular atrophy

article Full Text OpenAlex

m6A alters ribosome dynamics to initiate mRNA degradation

article Full Text OpenAlex

tRNA modifications tune m6A-dependent mRNA decay

article Full Text OpenAlex

STING aggravates ferroptosis-dependent myocardial ischemia-reperfusion injury by targeting GPX4 for autophagic degradation

article Full Text OpenAlex

Targeting epigenetic and post-translational modifications of NRF2: key regulatory factors in disease treatment

review Full Text OpenAlex

Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation

article Full Text OpenAlex

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis

article Full Text OpenAlex

TRAPT: a multi-stage fused deep learning framework for predicting transcriptional regulators based on large-scale epigenomic data

article Full Text OpenAlex

An ultrasensitive method for detection of cell-free RNA

article Full Text OpenAlex

近5年高被引文献
Ferroptosis: mechanisms, biology and role in disease

review Full Text OpenAlex 5099 FWCI173.692

Broadening horizons: the role of ferroptosis in cancer

review Full Text OpenAlex 2223 FWCI84.57

Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications

review Full Text OpenAlex 1965 FWCI119.068

UALCAN: An update to the integrated cancer data analysis platform

article Full Text OpenAlex 1643 FWCI155.522

Targeting ferroptosis as a vulnerability in cancer

review Full Text OpenAlex 1623 FWCI96.853

The role of m6A modification in the biological functions and diseases

review Full Text OpenAlex 1591 FWCI34.987

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

article Full Text OpenAlex 1583 FWCI106.787

PLIP 2021: expanding the scope of the protein–ligand interaction profiler to DNA and RNA

article Full Text OpenAlex 1484 FWCI86.629

Long non-coding RNAs: definitions, functions, challenges and recommendations

review Full Text OpenAlex 1429 FWCI89.644

Sotorasib for Lung Cancers with KRAS p.G12C Mutation

article Full Text OpenAlex 1366 FWCI90.754