专题：TGF-β signaling in diseases

This cluster of papers explores the diverse aspects of the Transforming Growth Factor Beta (TGF-ß) signaling pathway, including its role in Smad-dependent and Smad-independent pathways, tumor suppression, cancer progression, bone morphogenetic protein (BMP) signaling, immune response modulation, cell differentiation, metastasis, regulation of epithelial-mesenchymal transition (EMT), and angiogenesis. It also discusses the development and use of TGF-ß inhibitors for potential therapeutic interventions.
最新文献
BMP9-mediated regulation of endothelin-1 requires integrated SMAD1/5 and SMAD2/3 signaling

article Full Text OpenAlex

Expression patterns of growth differentiation factor 8 protein in ovarian follicles and the corpus luteum of domestic cats

article Full Text OpenAlex

374P Clinical and immunologic rationale for a multi-epitope immunomodulatory vaccine targeting TGFβ in pancreatic cancer

article Full Text OpenAlex

Electroacupuncture alleviates central post-stroke pain in rats by modulating miR-21-5p/TGF-β/Smads pathway

article Full Text OpenAlex

Morphogen activation in TNBC resistance.

preprint Full Text OpenAlex

435eP Targeting PGK1 sensitizes urothelial carcinoma to immunotherapy

article Full Text OpenAlex

CTHRC1/TGF-β/Smad axis serves as therapeutic targets in inhibiting oral squamous cell carcinoma by mediating ferroptosis

article Full Text OpenAlex

Modulation of Oncogenic NOTCH Signaling in Highly Aggressive Malignancies by Targeting the γ-Secretase Complex: A Systematic Review

preprint Full Text OpenAlex

Association of CTGF and TGF –ß1 With Glomerulus Fibrosis in Iraqi Diabetic Patients With Chronic Kidney Disease

article Full Text OpenAlex

Differential TGF-β1/SMAD4 Signaling Regulates PMN-MDSC Differentiation and Reshapes the Immune Microenvironment in Breast Cancer

article Full Text OpenAlex

近5年高被引文献
Targeting TGF-β signal transduction for fibrosis and cancer therapy

review Full Text OpenAlex 875 FWCI106.57789081

TGF-β signaling in health, disease and therapeutics

review Full Text OpenAlex 687 FWCI329.44959644

TGF-β signaling in health and disease

review Full Text OpenAlex 626 FWCI117.34369762

The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and disease

article Full Text OpenAlex 290 FWCI139.27169529

TGF-β in developmental and fibrogenic EMTs

review Full Text OpenAlex 252 FWCI37.09220909

Intricacies of TGF-β signaling in Treg and Th17 cell biology

review Full Text OpenAlex 230 FWCI42.70419376

Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within

review Full Text OpenAlex 195 FWCI23.75234749

Whole Aspect of Runx2 Functions in Skeletal Development

review Full Text OpenAlex 190 FWCI23.26007086

Epithelial cells activate fibroblasts to promote esophageal cancer development

article Full Text OpenAlex 158 FWCI30.07860604

Smad3 Signatures in Renal Inflammation and Fibrosis

review Full Text OpenAlex 154 FWCI32.72499189