专题：NF-κB Signaling Pathways

This cluster of papers explores the role of NF-?B signaling in inflammation, immunity, and cancer. It covers various aspects such as the regulation of NF-?B activity, the link between NF-?B and inflammatory diseases, the impact of NF-?B on cancer development and progression, and the crosstalk with other signaling pathways. The papers also discuss potential therapeutic strategies targeting the NF-?B pathway.
最新文献
Irg1-Mediated Inhibition of A20 Triggers NF-κB Signaling Cascade in Tilapia Macrophages during Early Immune Response

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Regulation of Mouse CK2α (Csnk2a1) Promoter Expression In Vitro and in Cell Lines

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P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway

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IL-36R Inhibitor – Spesolimab Highly Effective in the treatment of PASH Syndrome: Clinical Case with General Evidence Analysis

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Daratumumab-induced acute angle closure glaucoma: bone marrow transplantation as a possible risk factor and atropinization as a potential solution

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IκBζ: A Delicate Mediator in Skin Homeostasis

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“Dapagliflozin mitigates lipopolysaccharide-induced neuroinflammation through potential involvement of the IL-17A/GSK3β signaling pathway and modulation of inflammatory cytokines”

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DAPK3-Ablation Regulates the AMPK/mTOR-GPX4 Signaling Pathway to Affect Biological Functions of Staphylococcus aureus-Treated Bone Marrow Mesenchymal Stem Cells and Potentially Ameliorate Osteomyelitis

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Cleidocranial Dysplasia: A Serendipitous Finding with Clinical Insights

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Reviewer #1 (Public review): Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate

peer-review Full Text OpenAlex

近5年高被引文献
NF-κB in biology and targeted therapy: new insights and translational implications

article Full Text OpenAlex 612 FWCI323.426

NF-κB: At the Borders of Autoimmunity and Inflammation

review Full Text OpenAlex 428 FWCI11.795

Ubiquitination in the regulation of inflammatory cell death and cancer

review Full Text OpenAlex 349 FWCI7.666

NF‐κB signaling in inflammation and cancer

review Full Text OpenAlex 333 FWCI8.148

NF-κB: blending metabolism, immunity, and inflammation

review Full Text OpenAlex 314 FWCI14.265

BCL-2 protein family: attractive targets for cancer therapy

review Full Text OpenAlex 301 FWCI11.382

Quercetin Prevents LPS-Induced Oxidative Stress and Inflammation by Modulating NOX2/ROS/NF-kB in Lung Epithelial Cells

article Full Text OpenAlex 238 FWCI14.937

Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas

article Full Text OpenAlex 237 FWCI18.172

Targeting KRAS in non-small-cell lung cancer: recent progress and new approaches

review Full Text OpenAlex 234 FWCI8.965

Toll-Like Receptors (TLRs): Structure, Functions, Signaling, and Role of Their Polymorphisms in Colorectal Cancer Susceptibility

review Full Text OpenAlex 230 FWCI5.479