专题：NF-κB Signaling Pathways

This cluster of papers explores the role of NF-?B signaling in inflammation, immunity, and cancer. It covers various aspects such as the regulation of NF-?B activity, the link between NF-?B and inflammatory diseases, the impact of NF-?B on cancer development and progression, and the crosstalk with other signaling pathways. The papers also discuss potential therapeutic strategies targeting the NF-?B pathway.
最新文献
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers

article Full Text OpenAlex

Anti-Inflammatory Mechanism of Raddeanin A on RAW 264.7 Macrophage Inflammation Model Induced by LPS

article Full Text OpenAlex

Celastrol attenuates Th17 cell response through downregulating HDAC3/FOXO3/GLS1-dependent glutaminolysis

article Full Text OpenAlex

LGALS3BP Induces Insulin Resistance via TLR2-IKKα/β Pathway-Mediated IRS1 Serine Phosphorylation

article Full Text OpenAlex

O-GlcNAc transferase influences the progression of degenerative cartilage disease in lumbar facet joint osteoarthritis through FoxO1 and EGR1

article Full Text OpenAlex

Identification of novel candidate immune biomarkers linked to osteoclast activity during orthodontic tooth movement in a mouse model

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LRRK2 Kinase Mediates Increased GCase Activity in Microglia in Response to Proinflammatory Stimuli

preprint Full Text OpenAlex

Okanin attenuates ovariectomy-induced bone loss in mice model through inhibition of IKKβ-mediated NF-κB p65 phosphorylation

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Chromatin-associated cullin-RING E3 ubiquitin ligases: keeping transcriptionally active NF-κB in check

review Full Text OpenAlex

Assessment of the content of the nuclear transcription factor NF-kB in serum of patients with head and neck cancer depending on the clinical and morphological characteristics of the disease

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近5年高被引文献
NF-κB in biology and targeted therapy: new insights and translational implications

article Full Text OpenAlex 1257 FWCI713.86884457

NF-κB: blending metabolism, immunity, and inflammation

review Full Text OpenAlex 449 FWCI60.36469305

BCL-2 protein family: attractive targets for cancer therapy

review Full Text OpenAlex 427 FWCI51.93518467

The Pivotal Role of NF-kB in the Pathogenesis and Therapeutics of Alzheimer’s Disease

review Full Text OpenAlex 312 FWCI56.90034893

DNA damage and repair in age-related inflammation

review Full Text OpenAlex 305 FWCI34.83754882

Toll-like receptor 4 (TLR4): new insight immune and aging

review Full Text OpenAlex 275 FWCI53.33263868

Apoptosis: A Comprehensive Overview of Signaling Pathways, Morphological Changes, and Physiological Significance and Therapeutic Implications

review Full Text OpenAlex 267 FWCI128.22600911

Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice

article Full Text OpenAlex 233 FWCI110.09744236

Design of target specific peptide inhibitors using generative deep learning and molecular dynamics simulations

article Full Text OpenAlex 229 FWCI160.87292825

NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition

review Full Text OpenAlex 220 FWCI29.77447698