专题：NF-κB Signaling Pathways

This cluster of papers explores the role of NF-?B signaling in inflammation, immunity, and cancer. It covers various aspects such as the regulation of NF-?B activity, the link between NF-?B and inflammatory diseases, the impact of NF-?B on cancer development and progression, and the crosstalk with other signaling pathways. The papers also discuss potential therapeutic strategies targeting the NF-?B pathway.
最新文献
NF-κB in biology and targeted therapy: new insights and translational implications

article Full Text OpenAlex

Therapeutic compounds targeting interleukin-1 receptor-associated kinase 4 (IRAK4): an updated patent review (2019 to present)

review Full Text OpenAlex

Amlexanox targeted inhibition of TBK1 regulates immune cell function to exacerbate DSS-induced inflammatory bowel disease

article Full Text OpenAlex

Cylindromatosis lysine 63 deubiquitinase (CYLD) suppress TLR3-mediated CCL5 expression in human renal proximal tubular epithelial cells

article Full Text OpenAlex

Bioinformatic Analysis of IKK Complex Genes Expression in Selected Gastrointestinal Cancers

article Full Text OpenAlex

Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation

article Full Text OpenAlex

Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis

review Full Text OpenAlex

Pyroptosis of oral keratinocyte contributes to energy metabolic reprogramming of T cells in oral lichen planus via OPA1-mediated mitochondrial fusion

article Full Text OpenAlex

TFAP2A-activated ITGB4 promotes lung adenocarcinoma progression and inhibits CD4+/CD8+ T-cell infiltrations by targeting NF-κB signaling pathway

article Full Text OpenAlex

MARCH8 Mediates K27-Linked Polyubiquitination of IL-7 Receptor α to Negatively Regulate IL-7–Triggered T Cell Homeostasis

article Full Text OpenAlex

近5年高被引文献
NF-κB in biology and targeted therapy: new insights and translational implications

article Full Text OpenAlex 1119 FWCI635.49660865

NF-κB: At the Borders of Autoimmunity and Inflammation

review Full Text OpenAlex 522 FWCI39.6107769

Ubiquitination in the regulation of inflammatory cell death and cancer

review Full Text OpenAlex 440 FWCI30.13752002

NF-κB: blending metabolism, immunity, and inflammation

review Full Text OpenAlex 434 FWCI59.00512789

NF‐κB signaling in inflammation and cancer

review Full Text OpenAlex 431 FWCI26.37159541

BCL-2 protein family: attractive targets for cancer therapy

review Full Text OpenAlex 409 FWCI50.58142393

Quercetin Prevents LPS-Induced Oxidative Stress and Inflammation by Modulating NOX2/ROS/NF-kB in Lung Epithelial Cells

article Full Text OpenAlex 329 FWCI21.16453671

The Pivotal Role of NF-kB in the Pathogenesis and Therapeutics of Alzheimer’s Disease

review Full Text OpenAlex 295 FWCI55.10538524

Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas

article Full Text OpenAlex 289 FWCI20.3346412

DNA damage and repair in age-related inflammation

review Full Text OpenAlex 285 FWCI33.65661496