专题：Cyclopropane Reaction Mechanisms

This cluster of papers focuses on the catalytic carbene chemistry in organic synthesis, particularly on the use of donor-acceptor cyclopropanes, diazo compounds, and metal-catalyzed reactions. It covers topics such as enantioselective synthesis, site-selective functionalization, and the development of artificial metalloenzymes for carbene transfer reactions.
最新文献
Computational Mechanistic Investigation of Biocatalytic C(sp3)–H Insertions with Monosubstituted Carbenes via Engineered Heme Proteins

article Full Text OpenAlex

Synthesis of 3,3-oxaspirocycles via cobalt-catalyzed cascade C-H activation and carboamidation of alkynes

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Recent Advances in Asymmetric C—H Bond Functionalization Using Oxidizing Directing Groups

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Magnesium-Mediated Polymerization of Halogenated Phenyl-Substituted Arsonium Ylides for the Synthesis of Functionalized C3 Polymers

preprint Full Text OpenAlex

Sustainable, Ultrafast, and Solvent-Free Thiol–Ene Reactions Promoted by a Triazatruxene-Based Organocatalyst

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Rhodium(III)-Catalyzed Enantioselective Allylic C—H Alkylation of Unactivated Alkenes with α‑Diazocarbonyl Compounds

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Transition-Metal Free Synthesis of Cyclopropanone Ketals via Double Defluorinative Alkoxylation of gem-Difluorinated Cyclopropanes

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Blue Light-Induced Formal Insertion Reaction of α-Siloxy Carbene into C—H Bond of 1,3-Diketones

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Palladium-Catalyzed Addition of Allyl Fluorides to Gem-Difluoroolefins: Reorganization of C–F Bonds

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Copper-Catalyzed Formal C(sp3)–H Insertions via 1,5-Diyne Cyclization Triggered by a 1,6-Hydride Shift

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近5年高被引文献
Toolbox for Distal C–H Bond Functionalizations in Organic Molecules

review Full Text OpenAlex 395 FWCI7.933

Put a ring on it: application of small aliphatic rings in medicinal chemistry

review Full Text OpenAlex 302 FWCI6.203

Navigating the Unnatural Reaction Space: Directed Evolution of Heme Proteins for Selective Carbene and Nitrene Transfer

review Full Text OpenAlex 259 FWCI5.013

Sequential C–F bond functionalizations of trifluoroacetamides and acetates via spin-center shifts

article Full Text OpenAlex 249 FWCI21.648

Recent advances in transition-metal-catalyzed carbene insertion to C–H bonds

review Full Text OpenAlex 241 FWCI8.306

Iron- and Cobalt-Catalyzed Asymmetric Hydrofunctionalization of Alkenes and Alkynes

article Full Text OpenAlex 225 FWCI15.064

Lightening Diazo Compounds?

article Full Text OpenAlex 188 FWCI15.998

Carbon Atom Insertion into Pyrroles and Indoles Promoted by Chlorodiazirines

article Full Text OpenAlex 187 FWCI15.897

Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

review Full Text OpenAlex 185 FWCI4.569

From C4 to C7: Innovative Strategies for Site-Selective Functionalization of Indole C–H Bonds

article Full Text OpenAlex 183 FWCI16.764