专题：interferon and immune responses

This cluster of papers focuses on the innate immune response to viral infection, particularly the role of pattern recognition receptors such as RIG-I-like receptors and the cGAS-STING pathway in detecting viral nucleic acids and activating antiviral signaling. It also explores the mechanisms of interferon signaling, immune sensing of DNA and RNA viruses, and the regulation of antiviral responses.
最新文献
Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic life

article Full Text OpenAlex

80 years of extracellular vesicles: from discovery to clinical translation

article Full Text OpenAlex

Persistent T cell activation and cytotoxicity against glioblastoma following single oncolytic virus treatment in a clinical trial

article Full Text OpenAlex

2′-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity

article Full Text OpenAlex

PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling

article Full Text OpenAlex

Regulation of STING activation by phosphoinositide and cholesterol

article Full Text OpenAlex

Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332gp120 glycan-independent epitope

article Full Text OpenAlex

Biomimetic and personalized nanovaccines in cancer immunotherapy: Design innovations, translational challenges, and future directions

article Full Text OpenAlex

Human autoantibodies against type I interferons in severe viral disease

article Full Text OpenAlex

Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis

article Full Text OpenAlex

近5年高被引文献
NF-κB in biology and targeted therapy: new insights and translational implications

article Full Text OpenAlex 1593 FWCI429.3151

Notch signaling pathway: architecture, disease, and therapeutics

review Full Text OpenAlex 1009 FWCI131.0793

Mitochondrial control of inflammation

review Full Text OpenAlex 938 FWCI71.9357

cGAS–STING drives ageing-related inflammation and neurodegeneration

article Full Text OpenAlex 868 FWCI138.2422

A guide to cell death pathways

review Full Text OpenAlex 757 FWCI112.0576

Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling

article Full Text OpenAlex 704 FWCI52.5206

Context-specific regulation of extracellular vesicle biogenesis and cargo selection

review Full Text OpenAlex 684 FWCI102.7405

The JAK-STAT pathway at 30: Much learned, much more to do

review Full Text OpenAlex 643 FWCI58.6908

The cGAS–STING pathway and cancer

review Full Text OpenAlex 579 FWCI43.296

IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer

article Full Text OpenAlex 567 FWCI47.8983