专题：Congenital heart defects research

This cluster of papers explores the molecular mechanisms underlying cardiac development, regeneration, and congenital heart defects. It covers topics such as cardiomyocyte renewal, cardiac progenitor populations, endothelial cell-lineage analysis, neural crest contributions, epicardial progenitors, Wnt signaling, T-box genes, and the potential of microRNA therapy for cardiac regeneration.
最新文献
A single-cell time-lapse of mouse prenatal development from gastrula to birth

article Full Text OpenAlex

Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development

article Full Text OpenAlex

A Blueprint for Translational Precision Medicine in Autism Spectrum Disorder and Related Neurogenetic Syndromes

review Full Text OpenAlex

The 9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State

article Full Text OpenAlex

BRD4 as the key lactylation related gene in heart failure identified through bioinformatics analysis

article Full Text OpenAlex

Effects of embryonic origin, tissue cues and pathological signals on fibroblast diversity in humans

review Full Text OpenAlex

Role of Maternal Obesity in Offspring Cardiovascular Development and Congenital Heart Defects

article Full Text OpenAlex

MeCP2 and non-CG DNA methylation stabilize the expression of long genes that distinguish closely related neuron types

article Full Text OpenAlex

Lineage recording in monoclonal gastruloids reveals heritable modes of early development

preprint Full Text OpenAlex

Disrupted diencephalon development and neuropeptidergic pathways in zebrafish with autism-risk mutations

article Full Text OpenAlex

近5年高被引文献
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

review Full Text OpenAlex 571 FWCI145.76859346

Exome and genome sequencing for pediatric patients with congenital anomalies or intellectual disability: an evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG)

article Full Text OpenAlex 554 FWCI81.62947546

ACMG SF v3.0 list for reporting of secondary findings in clinical exome and genome sequencing: a policy statement of the American College of Medical Genetics and Genomics (ACMG)

article Full Text OpenAlex 528 FWCI89.49286529

Rare coding variation provides insight into the genetic architecture and phenotypic context of autism

review Full Text OpenAlex 520 FWCI93.10212952

Diagnosis and Evaluation of Hypertrophic Cardiomyopathy

review Full Text OpenAlex 481 FWCI106.2643622

Cardioids reveal self-organizing principles of human cardiogenesis

article Full Text OpenAlex 460 FWCI34.52647925

Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease

article Full Text OpenAlex 406 FWCI27.89427419

Human heart-forming organoids recapitulate early heart and foregut development

article Full Text OpenAlex 386 FWCI29.94245517

Histone Lactylation Boosts Reparative Gene Activation Post–Myocardial Infarction

article Full Text OpenAlex 369 FWCI82.45409017

Polygenic basis and biomedical consequences of telomere length variation

article Full Text OpenAlex 328 FWCI43.93099284