专题：Congenital heart defects research

This cluster of papers explores the molecular mechanisms underlying cardiac development, regeneration, and congenital heart defects. It covers topics such as cardiomyocyte renewal, cardiac progenitor populations, endothelial cell-lineage analysis, neural crest contributions, epicardial progenitors, Wnt signaling, T-box genes, and the potential of microRNA therapy for cardiac regeneration.
最新文献
Stem-Cell–Derived Biologic Ventricular Assist Tissue in Heart Failure

article Full Text OpenAlex

The microRNA inhibitor CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: a randomized phase 2 trial

article Full Text OpenAlex

A human specific CCG repeat in the RBFOX1 promoter is implicated in speech and autism

article Full Text OpenAlex

Mechanical load inhibits cancer growth in mouse and human hearts

article Full Text OpenAlex

Evolutionary origins and transcriptomic innovations of vertebrate Cajal-Retzius cells

article Full Text OpenAlex

Multiomics approaches to cardiovascular disease: technological innovations and clinical translation

article Full Text OpenAlex

Three-dimensional visualization of arrhythmogenic substrate in mouse hearts using panoramic optical mapping and micro-computed tomography

article Full Text OpenAlex

Targeting PPAR-γ Reduces Fibrosis and Arrhythmogenic Remodeling in DSG2-Linked Arrhythmogenic Cardiomyopathy

article Full Text OpenAlex

Genetic and Clinical Characterization of a South-Brazilian Hypertrophic Cardiomyopathy Cohort

article Full Text OpenAlex

The 2D : 4D Digit Ratio and Primary Sjögren's Syndrome: A Window Into Prenatal Hormonal Influences on Exocrine Autoimmunity

article Full Text OpenAlex

近5年高被引文献
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

review Full Text OpenAlex 691 FWCI110.0093

Rare coding variation provides insight into the genetic architecture and phenotypic context of autism

review Full Text OpenAlex 609 FWCI70.3946

Diagnosis and Evaluation of Hypertrophic Cardiomyopathy

review Full Text OpenAlex 578 FWCI83.6862

Histone Lactylation Boosts Reparative Gene Activation Post–Myocardial Infarction

article Full Text OpenAlex 483 FWCI65.3693

How vascular smooth muscle cell phenotype switching contributes to vascular disease

review Full Text OpenAlex 381 FWCI26.5054

Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction

article Full Text OpenAlex 361 FWCI75.871

Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration

article Full Text OpenAlex 306 FWCI24.9459

Global, regional, and national time trends in mortality for congenital heart disease, 1990–2019: An age-period-cohort analysis for the Global Burden of Disease 2019 study

article Full Text OpenAlex 267 FWCI37.3126

Embryo model completes gastrulation to neurulation and organogenesis

article Full Text OpenAlex 258 FWCI20.7017

Inhibition of fatty acid oxidation enables heart regeneration in adult mice

article Full Text OpenAlex 237 FWCI69.4284