专题：Congenital heart defects research

This cluster of papers explores the molecular mechanisms underlying cardiac development, regeneration, and congenital heart defects. It covers topics such as cardiomyocyte renewal, cardiac progenitor populations, endothelial cell-lineage analysis, neural crest contributions, epicardial progenitors, Wnt signaling, T-box genes, and the potential of microRNA therapy for cardiac regeneration.
最新文献
Mechanical load inhibits cancer growth in mouse and human hearts

article Full Text OpenAlex

Gut-Heart Axis in Myocardial Repair: Mechanisms, Cross-Organ Networks, and Therapeutic Opportunities

review Full Text OpenAlex

Dissecting gene regulatory networks governing human cortical cell fate

article Full Text OpenAlex

Molecular imaging of immune and fibrosis targets to guide therapy for repair after myocardial infarction

review Full Text OpenAlex

Engineered Regulatory T Lymphocytes Promote Infarcted Heart Repair

article Full Text OpenAlex

IDH2 lactylation promotes angiogenesis in murine diabetic myocardial infarction via blocking Cav1-eNOS interaction

article Full Text OpenAlex

Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy

article Full Text OpenAlex

Histone Lactylation Promotes Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure by Regulating TGFB2 Expression

article Full Text OpenAlex

S-Nitrosylation of Pyruvate Kinase Isoform 2 Drives Cardiac Fibrosis by Promoting Mitochondrial Fission

article Full Text OpenAlex

Succinate-driven PKM2 succinylation and dimerization accelerates age-associated cardiac fibrosis

article Full Text OpenAlex

近5年高被引文献

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CAR T Cells Produced in vivo to Treat Cardiac Injury

book-chapter Full Text OpenAlex 920 FWCI535.1077

Signaling pathways and targeted therapy for myocardial infarction

review Full Text OpenAlex 840 FWCI33.4174

Spatial multi-omic map of human myocardial infarction

article Full Text OpenAlex 769 FWCI42.7966

Histone Lactylation Boosts Reparative Gene Activation Post–Myocardial Infarction

article Full Text OpenAlex 569 FWCI65.0857

Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure

article Full Text OpenAlex 477 FWCI28.5038

Spatially resolved multiomics of human cardiac niches

article Full Text OpenAlex 422 FWCI38.5904

Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction

article Full Text OpenAlex 409 FWCI81.2147

Targeting immune–fibroblast cell communication in heart failure

article Full Text OpenAlex 317 FWCI92.9361

Nadas' Pediatric Cardiology

book Full Text OpenAlex 307 FWCI5.1867

α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure

article Full Text OpenAlex 297 FWCI59.5707