专题：Histone Deacetylase Inhibitors Research

This cluster of papers explores the role of histone deacetylases (HDACs) in regulating cellular functions, gene expression, and epigenetic modifications. It covers the use of HDAC inhibitors in cancer therapy, their impact on neurodegenerative disorders, and their involvement in protein complexes and enzymatic activity.
最新文献
Epigenetic regulators in cancer therapy and progression

review Full Text OpenAlex

Therapeutic potential of targeting the NEDD4L-eEF1A1 axis in cancer therapy

article Full Text OpenAlex

USP10 promotes the progression and attenuates gemcitabine chemotherapy sensitivity via stabilizing PLK1 in PDAC

article Full Text OpenAlex

Metabolic Reprogramming in Melanoma: An Epigenetic Point of View

review Full Text OpenAlex

Moving Away From Standard Induction in Newly Diagnosed Acute Myeloid Leukemia

review Full Text OpenAlex

NOTCH1 signaling is dysregulated by loss of the deubiquitinase USP28 with del(11q), uncovering USP28 inhibition as novel therapeutic target in CLL

article Full Text OpenAlex

Vepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer

article Full Text OpenAlex

Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights

review Full Text OpenAlex

Epigenetic Drivers of Atrial Fibrillation: Mechanisms, Biomarkers, and Therapeutic Targets

review Full Text OpenAlex

Belantamab mafodotin plus lenalidomide/dexamethasone in newly diagnosed intermediate-fit & frail multiple myeloma patients: Long-term efficacy and safety from the phase 1/2 BELARD clinical trial.

article Full Text OpenAlex

近5年高被引文献
Modulation of cellular processes by histone and non-histone protein acetylation

review Full Text OpenAlex 607 FWCI20.901

Metabolic reprogramming and epigenetic modifications on the path to cancer

review Full Text OpenAlex 520 FWCI10.657

Natural Products in Cancer Therapy: Past, Present and Future

review Full Text OpenAlex 512 FWCI11.916

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

article Full Text OpenAlex 409 FWCI37.935

Epigenetic mechanisms in breast cancer therapy and resistance

review Full Text OpenAlex 370 FWCI8.754

Ivosidenib and Azacitidine in IDH1 -Mutated Acute Myeloid Leukemia

article Full Text OpenAlex 368 FWCI78.964

MYC as a target for cancer treatment

review Full Text OpenAlex 363 FWCI8.315

Targeted protein degraders crowd into the clinic

review Full Text OpenAlex 358 FWCI9.574

Advances in acute myeloid leukemia

review Full Text OpenAlex 347 FWCI14.198

Meta-hallmarks of aging and cancer

review Full Text OpenAlex 327 FWCI23.141