专题：Histone Deacetylase Inhibitors Research

This cluster of papers explores the role of histone deacetylases (HDACs) in regulating cellular functions, gene expression, and epigenetic modifications. It covers the use of HDAC inhibitors in cancer therapy, their impact on neurodegenerative disorders, and their involvement in protein complexes and enzymatic activity.
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Modulation of cellular processes by histone and non-histone protein acetylation

review Full Text OpenAlex 942 FWCI15.6927

The sirtuin family in health and disease

article Full Text OpenAlex 869 FWCI77.0277

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

article Full Text OpenAlex 827 FWCI35.8781

Regulation of SIRT1 and Its Roles in Inflammation

article Full Text OpenAlex 700 FWCI65.0483

Epigenetics-targeted drugs: current paradigms and future challenges

article Full Text OpenAlex 347 FWCI39.8042

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

article Full Text OpenAlex 318 FWCI47.9608

Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents

article Full Text OpenAlex 263 FWCI13.5947

SIRT3‐dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth

article Full Text OpenAlex 253 FWCI32.9477

Lactate, histone lactylation and cancer hallmarks

article Full Text OpenAlex 213 FWCI20.5606

Targeting histone deacetylases for cancer therapy: Trends and challenges

article Full Text OpenAlex 209 FWCI15.5677