专题：Histone Deacetylase Inhibitors Research

This cluster of papers explores the role of histone deacetylases (HDACs) in regulating cellular functions, gene expression, and epigenetic modifications. It covers the use of HDAC inhibitors in cancer therapy, their impact on neurodegenerative disorders, and their involvement in protein complexes and enzymatic activity.
最新文献
Research progress on cancer-related epigenetic switches

review Full Text OpenAlex

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

review Full Text OpenAlex

Vepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer

article Full Text OpenAlex

Analysis of Epigenome-Wide Association Studies

article Full Text OpenAlex

The study of Histone Deacetylases Immunoexpression in relation to Regulating Vascular Endothelial Growth Factor (VEGF) Implicated in Malignant Progression of Colorectal cancer

article Full Text OpenAlex

Efficacy and safety of entinostat plus exemestane in hormone receptor-positive breast cancer: a systematic review meta-analysis of randomized controlled trials

review Full Text OpenAlex

Design, synthesis, and biological evaluation of indazole-based histone deacetylase 6 inhibitors

article Full Text OpenAlex

A Phase 2 Trial of CPX‐351 Combined With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia

article Full Text OpenAlex

Synthesis of spiro[cyclopropane-isatin] derivatives and their therapeutic potential as anticancer agents against colorectal carcinoma

article Full Text OpenAlex

Treatment-related adverse events, immune-related adverse events and discontinuation in patients with solid tumors adding adjuvant immune checkpoint blockade: a meta-analysis of 38 randomized controlled trials

article Full Text OpenAlex

近5年高被引文献
Modulation of cellular processes by histone and non-histone protein acetylation

review Full Text OpenAlex 542 FWCI20.458

Natural Products in Cancer Therapy: Past, Present and Future

review Full Text OpenAlex 489 FWCI11.88

Metabolic reprogramming and epigenetic modifications on the path to cancer

review Full Text OpenAlex 481 FWCI10.651

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

article Full Text OpenAlex 374 FWCI36.014

Targeted protein degraders crowd into the clinic

review Full Text OpenAlex 350 FWCI9.578

MYC as a target for cancer treatment

review Full Text OpenAlex 347 FWCI8.31

Epigenetic mechanisms in breast cancer therapy and resistance

review Full Text OpenAlex 343 FWCI8.749

Ivosidenib and Azacitidine in IDH1 -Mutated Acute Myeloid Leukemia

article Full Text OpenAlex 338 FWCI78.867

Advances in acute myeloid leukemia

review Full Text OpenAlex 331 FWCI14.213

Meta-hallmarks of aging and cancer

review Full Text OpenAlex 312 FWCI23.757