专题:Histone Deacetylase Inhibitors Research

This cluster of papers explores the role of histone deacetylases (HDACs) in regulating cellular functions, gene expression, and epigenetic modifications. It covers the use of HDAC inhibitors in cancer therapy, their impact on neurodegenerative disorders, and their involvement in protein complexes and enzymatic activity.
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Deciphering epigenetic crosstalk in multiple myeloma pathogenesis and treatment

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New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs

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Systemic epigenetic dysregulation as a driver of ageing and a therapeutic target

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Histone deacetylases and cell-cycle regulators orchestrate cell-identity transitions during Arabidopsis root regeneration

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Lactate metabolism and protein lactylation in cancer

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Clinical and Pathological Characteristics of Stage IV SMARCA4-Deficient Lung Cancer and the Efficacy of Immune Checkpoint Inhibitors

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Targeted Protein Degradation in Cancer: PROTACs, New Targets, and Clinical Mechanisms

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Discovery of Potent HDAC6-Selective Inhibitors Based on Artemisinin: Design, Synthesis, and Antitumor Evaluation

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Current opinion in cardiology, epigenetics of heart failure

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Advances in the Understanding of Akt Signaling in Cancers and the Potential of Inhibiting Akt-Driven Tumors Using Small Molecule Inhibitors: An Overview

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