专题：Nicotinic Acetylcholine Receptors Study

This cluster of papers focuses on the structure and function of nicotinic acetylcholine receptors, including their crystal structures, neuronal signaling mechanisms, allosteric modulation, and their role in cognitive function, ion channel activity, the cholinergic system, brain reward areas, schizophrenia, and Alzheimer's disease.
最新文献
Molecular mechanism of calcium permeability and magnesium block in NMDA receptors

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Therapeutic Potential of Glucagon-Like Peptide-1 Receptor Agonists for Smoking Cessation

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Toxicity, Chemistry, and Public Health Relevance of Emerging Nicotine Analog Vapes, Pods, and Pouches

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Synchronous activation of striatal cholinergic interneurons induces local serotonin release

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Nicotinic acetylcholine receptors-targeting drug discovery

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Structural basis for activation and conformational plasticity of the GluA4 AMPA receptor

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Structures of the honeybee GABAA RDL receptor illuminate allosteric modulation

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Cholinergic modulation of dopamine release drives effortful behaviour

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A trans-synaptic IgLON adhesion molecular complex directly contacts and clusters a nicotinic receptor

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Knockout of nAChR subunits in spider mites and their phytoseiid predators confers spinosyn cross-resistance and reveals a conserved mode of action in mites

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近5年高被引文献
An action potential initiation mechanism in distal axons for the control of dopamine release

article Full Text OpenAlex 212 FWCI17.5462

Basal forebrain cholinergic signalling: development, connectivity and roles in cognition

review Full Text OpenAlex 144 FWCI5.6462

Nicotine on the developing brain

article Full Text OpenAlex 141 FWCI20.269

Nicotinic acetylcholine receptor modulator insecticides act on diverse receptor subtypes with distinct subunit compositions

article Full Text OpenAlex 130 FWCI6.6254

Neurobiological Mechanisms of Nicotine Reward and Aversion

article Full Text OpenAlex 122 FWCI5.8662

Structural biology and molecular pharmacology of voltage-gated ion channels

review Full Text OpenAlex 117 FWCI5.0682

Levels of nicotine and tobacco-specific nitrosamines in oral nicotine pouches

article Full Text OpenAlex 117 FWCI11.2601

Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective

article Full Text OpenAlex 113 FWCI6.7262

Differential assembly diversifies GABAA receptor structures and signalling

article Full Text OpenAlex 111 FWCI8.2138

Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities

article Full Text OpenAlex 104 FWCI7.4811