专题：Barrier Structure and Function Studies

This cluster of papers focuses on the structure, function, and dysfunction of the blood-brain barrier, as well as the interactions between astrocytes, endothelial cells, and pericytes in the neurovascular unit. It covers topics such as tight junctions, CNS drug delivery, neurological diseases, and the role of various cell types in maintaining vascular homeostasis.
最新文献
Kynu inhibition mitigates bile duct ischemic injury by rewiring tryptophan metabolism to restore tight junction integrity

article Full Text OpenAlex

Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging

article Full Text OpenAlex

The expression of the tight junction protein and therapeutical target Claudin 18.2 is heterogeneously distributed within esophageal and gastric adenocarcinoma

article Full Text OpenAlex

Connexin 43 inhibitors reduce cell viability in glioblastoma and astrocyte co-culture systems

article Full Text OpenAlex

Muscone Ameliorates Cerebral Ischemia-Reperfusion-Induced Bbb Injury Through Pka/Rhoa/Mlc Pathway

preprint Full Text OpenAlex

Spef1 is a microvillar component that limits apical actomyosin contractility and preserves intestinal barrier function

preprint Full Text OpenAlex

Pericytes from individuals with multiple sclerosis show reduced contractility but remain responsive to myelin debris, hypoxia, and inflammatory cytokines

preprint Full Text OpenAlex

Targeting complement C3 with Tanshinone I decreases microglia-mediated synaptic engulfment to exert antidepressant effects

article Full Text OpenAlex

Cerebral Haemodynamics and White Matter Hyperintensities: Findings Using Non-Invasive Brain Imaging

preprint Full Text OpenAlex

Vascular Microforamina in Adult Human Braincase: A Survey on Dry Skulls

article Full Text OpenAlex

近5年高被引文献
The blood–brain barrier: Structure, regulation and drug delivery

review Full Text OpenAlex 800 FWCI49.098

A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk

article Full Text OpenAlex 584 FWCI63.508

Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities

review Full Text OpenAlex 553 FWCI19.384

Revisiting the neurovascular unit

review Full Text OpenAlex 474 FWCI12.607

The blood-brain barrier in aging and neurodegeneration

review Full Text OpenAlex 441 FWCI15.522

The blood–brain barrier in systemic infection and inflammation

review Full Text OpenAlex 437 FWCI10.704

Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial

article Full Text OpenAlex 421 FWCI79.948

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

review Full Text OpenAlex 398 FWCI9.549

Paracellular permeability and tight junction regulation in gut health and disease

review Full Text OpenAlex 376 FWCI23.079

Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

article Full Text OpenAlex 373 FWCI22.416