专题：Barrier Structure and Function Studies

This cluster of papers focuses on the structure, function, and dysfunction of the blood-brain barrier, as well as the interactions between astrocytes, endothelial cells, and pericytes in the neurovascular unit. It covers topics such as tight junctions, CNS drug delivery, neurological diseases, and the role of various cell types in maintaining vascular homeostasis.
最新文献
Functionalized Nanomaterials Capable of Crossing the Blood–Brain Barrier

review Full Text OpenAlex

Farnesol ameliorates DSS-induced IBD by regulating inflammatory cytokines, repairing the intestinal barrier, reversing the gut microbiota imbalance, and influencing fecal metabolome in C57BL/6 mice

article Full Text OpenAlex

Role of tight junction proteins in shaping the immune milieu of malignancies

review Full Text OpenAlex

Intestinal Akkermansia muciniphila is Beneficial to Functional Recovery Following Ischemic Stroke

article Full Text OpenAlex

Dietary limonene promotes gastrointestinal barrier function via upregulating tight/adherens junction proteins through cannabinoid receptor type‐1 antagonistic mechanism and alters cellular metabolism in intestinal epithelial cells

article Full Text OpenAlex

Diffusion magnetic resonance spectroscopy captures microglial reactivity related to gut-derived systemic lipopolysaccharide: A preliminary study

article Full Text OpenAlex

T Cells Trafficking into the Brain in Aging and Alzheimer’s Disease

review Full Text OpenAlex

Paracellular barriers: Advances in assessing their contribution to renal epithelial function

review Full Text OpenAlex

721MO Phase I, two-part, multicenter first-in-human (FIH) study of TORL-1-23: A novel claudin 6 (CLDN6) targeting antibody drug conjugate (ADC) in patient with advanced solid tumors

article Full Text OpenAlex

1456P First in human phase I/II trial of claudin 18.2 ADC RC118 in patients with advanced gastric/gastroesophageal junction cancer

article Full Text OpenAlex

近5年高被引文献
The blood–brain barrier: Structure, regulation and drug delivery

review Full Text OpenAlex 1111 FWCI246.72567084

A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk

article Full Text OpenAlex 702 FWCI96.34819406

Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities

review Full Text OpenAlex 687 FWCI93.52233921

The blood-brain barrier in aging and neurodegeneration

review Full Text OpenAlex 553 FWCI74.41417782

Revisiting the neurovascular unit

review Full Text OpenAlex 542 FWCI48.27581538

The blood–brain barrier in systemic infection and inflammation

review Full Text OpenAlex 528 FWCI41.56028201

Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial

article Full Text OpenAlex 523 FWCI116.25002329

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

review Full Text OpenAlex 499 FWCI39.53295118

Paracellular permeability and tight junction regulation in gut health and disease

review Full Text OpenAlex 471 FWCI104.69170357

Microglia use TAM receptors to detect and engulf amyloid β plaques

article Full Text OpenAlex 438 FWCI43.71432101