专题:Redox biology and oxidative stress

This cluster of papers explores the role of reactive oxygen species (ROS) and redox signaling in cellular processes, focusing on mechanisms of redox regulation, oxidative stress, and the involvement of antioxidant systems such as thioredoxin and peroxiredoxins. It delves into the signaling functions of hydrogen peroxide, glutathione catalysis, protein carbonylation, and the maintenance of cellular redox homeostasis.
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Co-targeting cystathionine gamma-lyase and mTOR: a promising therapeutic strategy in clear cell ovarian cancer

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Cytosolic PRDX1 acts as an extramitochondrial sink to set mitochondrial H2O2 levels and enable resilience to chronic mitochondrial oxidative stress

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Deciphering glyoxalase gene families and their coordinated regulation with the ascorbate–glutathione cycle during salinity stress in Artemisia annua

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Don’t Lose Your (War)head: Structure–Activity Relationships of Covalent Warheads as Substrates for GST-Catalyzed Glutathione Conjugation

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Early ADME and Preliminary Toxicity Studies of I-152, an N -Acetyl- l -Cysteine/ S -Acetylcysteamine Conjugate

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Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

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Mutations in the Txnip PPXY motifs protect against myocardial infarction despite enhanced protein stability

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A rapid HPLC method to simultaneously quantify therapeutic thiols and monitor their disulfide exchange reactions with cystine

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Mechanistic and Structural Analysis of Aflatoxin B1 Degradation by Bacillus safensis Multicopper Oxidase

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SLC25A21 promotes ferroptosis by inducing mitochondrial GPX4 deficiency in colorectal cancer

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