专题：Hippo pathway signaling and YAP/TAZ

This cluster of papers explores the role of the Hippo signaling pathway, particularly the involvement of YAP/TAZ, in mechanotransduction, cell proliferation, tissue growth control, organ size control, and its implications in cancer and stem cell regulation.
最新文献
Ginsenoside Rh3 enhances regorafenib efficacy in hepatocellular carcinoma by modulating FGFR4-STAT3-YAP signaling pathway

article Full Text OpenAlex

Modelling EWS::FLI1 protein fluctuations reveal determinants of tumor plasticity in Ewing sarcoma

article Full Text OpenAlex

DynamicAtlas: a morphodynamic atlas for Drosophila development

article Full Text OpenAlex

Matrix stiffness drives squamous cell carcinoma progression via a Piezo1-mediated mechanotransduction feedback loop

article Full Text OpenAlex

Phenotype switching in highly invasive resistant to vemurafenib and cobimetinib melanoma cells

article Full Text OpenAlex

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway–dependent Rho/ROCK signaling

article Full Text OpenAlex

YAP/TEAD inhibitor VT3989 in solid tumors: a phase 1/2 trial

article Full Text OpenAlex

Netrin-1 upregulates the its own gene expression and unc5b gene expression, but downregulates ccl19 gene expression in human macrophages THP-1 cell line

article Full Text OpenAlex

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

article Full Text OpenAlex

Substrate Stiffness Regulates the Osteogenesis of PDLSCs Via ERK-Mediated YAP Nuclear Translocation

article Full Text OpenAlex

近5年高被引文献
The Hippo signalling pathway and its implications in human health and diseases

review Full Text OpenAlex 571 FWCI93.21527176

Mechanical regulation of bone remodeling

review Full Text OpenAlex 465 FWCI74.7681164

Tissue geometry drives deterministic organoid patterning

article Full Text OpenAlex 446 FWCI67.18307751

Extracellular fluid viscosity enhances cell migration and cancer dissemination

article Full Text OpenAlex 362 FWCI58.93294764

YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS–STING

article Full Text OpenAlex 292 FWCI47.17900795

The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer

review Full Text OpenAlex 280 FWCI45.70976548

Cancer cell plasticity during tumor progression, metastasis and response to therapy

review Full Text OpenAlex 264 FWCI62.72561501

N6-Methyladenosine–Mediated Up-Regulation of FZD10 Regulates Liver Cancer Stem Cells’ Properties and Lenvatinib Resistance Through WNT/β-Catenin and Hippo Signaling Pathways

article Full Text OpenAlex 257 FWCI47.71729476

Towards targeting of shared mechanisms of cancer metastasis and therapy resistance

review Full Text OpenAlex 256 FWCI38.28392665

Apical–basal polarity and the control of epithelial form and function

review Full Text OpenAlex 247 FWCI39.17979899