专题：Hippo pathway signaling and YAP/TAZ

This cluster of papers explores the role of the Hippo signaling pathway, particularly the involvement of YAP/TAZ, in mechanotransduction, cell proliferation, tissue growth control, organ size control, and its implications in cancer and stem cell regulation.
最新文献
Covalent pan-TEAD inhibitors block YAP activity and demonstrate brain penetrance in a Hippo-dependent cancer model

article Full Text OpenAlex

Sensing centrosome amplification: the interface between centriole duplication and autophagy

article Full Text OpenAlex

Cancer-associated adipomes promote invadopodia formation and enhance metastatic potential in triple-negative breast cancer

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Succinate drives breast cancer bone metastasis by activating the HIF1α/YTHDF1/YAP signaling axis to upregulate chemokine CXCL5 and disrupt the bone microenvironment

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Role of YAP/TAZ Mechanobiological Signaling in Osteoporosis and Osteoarthritis

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The cellular ecosystem of skeletal muscle regeneration: molecular mechanisms, pathological disorders, and potential therapeutic strategies

article Full Text OpenAlex

Hui‐Xiang Decoction Against Pancreatic Cancer by Regulating AKT and Activating the Hippo Signaling Pathway

article Full Text OpenAlex

Epithelial-to-mesenchymal transition as a central driver of tumor cell plasticity

article Full Text OpenAlex

Seven complete comparative maps of allosteric mutations in a protein family

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Comprehensive profiling of clinically approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing

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近5年高被引文献
The Hippo signalling pathway and its implications in human health and diseases

article Full Text OpenAlex 729 FWCI61.3207

Mechanical regulation of bone remodeling

article Full Text OpenAlex 602 FWCI49.2928

Tissue geometry drives deterministic organoid patterning

article Full Text OpenAlex 505 FWCI41.7386

Extracellular fluid viscosity enhances cell migration and cancer dissemination

article Full Text OpenAlex 420 FWCI38.8758

Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets

article Full Text OpenAlex 383 FWCI67.7379

YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS–STING

article Full Text OpenAlex 345 FWCI31.0362

The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer

article Full Text OpenAlex 334 FWCI30.2142

Cancer cell plasticity during tumor progression, metastasis and response to therapy

article Full Text OpenAlex 326 FWCI37.1367

The alanyl-tRNA synthetase AARS1 moonlights as a lactyltransferase to promote YAP signaling in gastric cancer

article Full Text OpenAlex 298 FWCI67.5108

Apical–basal polarity and the control of epithelial form and function

article Full Text OpenAlex 298 FWCI25.3445